Results 51 to 60 of about 4,926,174 (297)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Development of a user-friendly interface routine in C++ for arithmetic and statistical processing of census data - doi: 10.4025/actascitechnol.v35i1.13618

open access: yesActa Scientiarum: Technology, 2013
A routine was developed in C++ for the processing of social and environmental census data acquired by the Brazilian Institute of Geography and Statistics (IBGE). The routine employs a simple graphical environment.
Roberto Wagner Lourenço   +4 more
doaj   +1 more source

Punctuated Equilibrium in Software Evolution

open access: yes, 2003
The approach based on paradigm of self-organized criticality proposed for experimental investigation and theoretical modelling of software evolution. The dynamics of modifications studied for three free, open source programs Mozilla, Free-BSD and Emacs ...
A. A. Gorshenev   +9 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Reviews of Free Statistical Software [PDF]

open access: yesInterdisciplinary Journal of Virtual Learning in Medical Sciences, 2014
Nowadays the use of statistical software is obvious to conduct scientific research. Select statistical software according to moral considerations requires payment of fees.
Rahil Hakimimofrad, Reza Hakimimofrad
doaj  

Commons Praxis: Toward a Critical Political Economy of the Digital Commons

open access: yestripleC: Communication, Capitalism & Critique, 2018
The concept of the commons has provided a useful framework for understanding a wide range of resources and cultural activities associated with the creation of value outside of the traditional market mechanisms under capitalism (i.e., private property ...
Benjamin J Birkinbine
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Learning free software using cloud services

open access: yesCTE Workshop Proceedings, 2020
The article deals with the use of cloud technology services in the study of free software. Free software is a social phenomenon based on the philosophy of freedom and the right to intellectual creative activity. To date, a significant number of software
Elena H. Fedorenko   +3 more
doaj   +1 more source

Free Software without a Free Lunch or Free Beer [PDF]

open access: yesIEEE Micro, 2018
Economists like to say that there are no free lunches. How does that attitude apply to free software and services?
openaire   +1 more source

Using Data and Statistics [PDF]

open access: yes, 2019
This handout identifies the differences between statistics and data and how to use and analyze them. It provides numerous links to data and statistic sources available for free online or as part of our library subscriptions.
Miller, Randy L
core   +1 more source

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