Results 71 to 80 of about 4,926,174 (297)
BIM Open Source Software (OSS) for the documentation of cultural heritage
Virtual Archaeology Review, 2016 The Building Information Modelling (BIM) software enables the users to communicate and design, understand appearance, performance and cost in the spatial and urban design process.
Sotiris Logothetis +1 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Free Software’s Market-Oriented Aspects:The Example of Free Software Service Companies in France [PDF]
Considering the french case of Free Software Service Companies (FSSCs), this paper analyses Free software’s market-oriented aspects. We try to answer a fundamental question for free software: is the software industry have room for an alternative economic
Marie CORIS (E3i-IFReDE-GRES)
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
MODELANDO LA TOMA DE DECISIONES MEDIANTE FUSIO ́N DE CREENCIAS
Rect@, 2014 Belief merging is a relatively recent technique with the aim of combining pieces of infor- mation, possibly inconsistent, coming from different sources.
Chávez-Bosquez, Oscar +1 more
doaj
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Modularity in action.GNU/Linux and free/Open source sotfware development model unleashed. [PDF]
Organizational and managerial theories of modularity applied to the design and production of complex artifacts are used to interpret the rise and success of Free/Open Source Software methodologies and practices in software engineeringmodularity; software
Alessandro Narduzzo, Alessandro Rossi
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Open Source Software: Why is it here and will it stick around?
SCRIPTed: A Journal of Law, Technology & Society, 2004 This paper discusses the details behind the Open Source Software development scheme by looking at some of the most prevalent licences, and then by asking the question of whether Open Source will survive the legal battles that are starting to affect it ...
Kimmo Nikulainen
doaj
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source