Results 71 to 80 of about 2,170,936 (313)
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
The Economics of Free and Open Source Software: Contributions to a Government Policy on Open Source Software [PDF]
This document seeks to lay the groundwork for a government policy on free and open source software. We briefly characterize the extent of the open source software phenomenon.
Jacques Robert, Marcel Boyer
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Free software, an alternative to reduce the use of non-licensed proprietary software in the MSMEs in the city of Montería [PDF]
, 2013 El software libre es sin duda, es la punta de lanza de un modelo de mayor dimensión que prioriza y potencia una apuesta por la transparencia, la independencia, la colaboración y la racionalización de los recursos.
Vergara Villadiego, Juan Raúl
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Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
MODELANDO LA TOMA DE DECISIONES MEDIANTE FUSIO ́N DE CREENCIAS
Rect@, 2014 Belief merging is a relatively recent technique with the aim of combining pieces of infor- mation, possibly inconsistent, coming from different sources.
Chávez-Bosquez, Oscar +1 more
doaj
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Design and implementation of a model of migration from proprietary software to free software and application of open source technologies for educational institutions in the department of Chocó [PDF]
, 2009 El proyecto DISEÑO E IMPLEMENTACIÓN DE UN MODELO DE MIGRACIÓN DE SOFTWARE PROPIETARIO A SOFTWARE LIBRE Y APLICACIÓN DE TECNOLOGÍAS DE CÓDIGO ABIERTO PARA LAS INSTITUCIONES EDUCATIVAS DEL DEPARTAMENTO DEL CHOCÓ está orientado a obtener un conocimiento ...
Mena Palacios, José Faustin +2 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Free Software Movement and the GNU/Linux Operating System
, 2003 Richard Stallman will speak about the purpose, goals, philosophy, methods, status, and future prospects of the GNU operating system, which in combination with the kernel Linux is now used by an estimated 17 to 20 million users world wide.BiographyRichard
Richard Stallman (the Free Software Foundation)
core
, 2014 Challenges related to development, deployment, and maintenance of reusable software for science are becoming a growing concern. Many scientists’ research increasingly depends on the quality and availability of software upon which their works are built ...
Ketan Maheshwari +35 more
core +1 more source