Results 91 to 100 of about 4,926,174 (297)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Public Libraries: techno trends and collective memory [PDF]

open access: yes, 2009
By public library I mean here a library providing some kind of universal access to its assets, one whose readership isn’t exclusively tied and restricted to a particular organization – including the generally called public libraries, but also many ...
Dias, Miguel   +1 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Comentaris breus sobre la GNU General Public License v3

open access: yesIDP, 2009
La llicència GNU General Public License és la llicència de programari lliure més utilitzada i constitueix un document fonamental per al moviment de programari lliure.
Malcolm Bain
doaj   +1 more source

free qsar software

open access: yes, 2020
https://www.profacgen.com/3D-QSAR ...
openaire   +1 more source

Transiently Consistent SDN Updates: Being Greedy is Hard

open access: yes, 2016
The software-defined networking paradigm introduces interesting opportunities to operate networks in a more flexible, optimized, yet formally verifiable manner. Despite the logically centralized control, however, a Software-Defined Network (SDN) is still
Amiri, Saeed Akhoondian   +3 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Open software in small enterprises. Private medical practise example

open access: yesContemporary Economy, 2011
Article covers basic concepts of free and open software and its implementation at small health care facilities. It summarizes costs of possession and maintenance free/open and proprietary software.
Dominik Meller
doaj  

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