Results 111 to 120 of about 2,170,936 (313)
INSPECTOR: free software for magnetic resonance spectroscopy data inspection, processing, simulation and analysis. [PDF]
Gajdošík M +3 more
europepmc +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The Free Software Foundation (FSF) was established in 1985 to promote "computer users' rights to use, study, copy, modify, and redistribute computer programs." That is, the organization promotes the development and use of free software ...
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Open source software and the library community
This paper examines whether the library community should support the development of open source software, software whose licensing allows its source code, the part of a computer program that is readable by humans, to be redistributed and/or modified ...
Clarke, Kevin S., Clarke, Kevin
core +1 more source
Free software for free access to information
Georgina Araceli Torres Vargas and Juan Manuel Zurita Sánchez, Software libre y libre accesso a la información : ¿Hacia un ciberespacio público? in <i> Documentación de las Ciencias de la Información </i> 30 (2007) pp. 135-148. Self-archived today.
openaire +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Free Open Source Software and Dual-Use: Loophole or Dissent?
The Free Open Source Software (FOSS) seem far from the military field but in some cases, some technologies normally used for civilian purposes may have military applications. These products and technologies are called dual-use.
Foutel, Nathalie
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Comparative properties analysis of open, free and commercial software
У статті проводиться порівняння програмних продуктів, що взяті на безкоштовній основі, програмних продуктів, що поширюються за вільними ліцензіями із відкритим кодом, та комерційних розробок.
Великодний, С. С. +3 more
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