Results 131 to 140 of about 8,338,277 (309)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Columbus Free Press subscription letter
, 1990 Form letter encouraging subscription to and financial support for the Columbus Free Press, dated January 1990 as the publication was celebrating its 20th anniversary. The Columbus Free Press began as a bi-weekly publication in Columbus, Ohio, in 1970.
Columbus Free Press (Publisher)
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Revista Cubana de Investigaciones Biomédicas, 2010 Con el fin de estimular el uso de R en la investigación clínica y a partir de la experiencia con este software para el procesamiento y análisis de datos, se muestran algunas de sus características y las principales ventajas que ofrece su utilización en ...
MayelÍn Mirabal Sosa +2 more
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Design and implementation of a model of migration from proprietary software to free software and application of open source technologies for educational institutions in the department of Chocó [PDF]
, 2009 El proyecto DISEÑO E IMPLEMENTACIÓN DE UN MODELO DE MIGRACIÓN DE SOFTWARE PROPIETARIO A SOFTWARE LIBRE Y APLICACIÓN DE TECNOLOGÍAS DE CÓDIGO ABIERTO PARA LAS INSTITUCIONES EDUCATIVAS DEL DEPARTAMENTO DEL CHOCÓ está orientado a obtener un conocimiento ...
Mena Palacios, José Faustin +2 more
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Revista Fuentes El Reventón Energético, 2009 This paper shows the implementation of a neurosimulation technique for the well placement applied to the development of a heterogeneous hydrocarbon field with an irregular geometry.
Elkin Rodolfo Santafe Rangel +1 more
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Structure-based drug design of an inhibitor of the SARS-CoV-2 (COVID-19) main protease using free software: A tutorial for students and scientists. [PDF]
Eur J Med Chem, 2021 Zhang S +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Contracting with free software communities
Industry and large Agencies needs ¿agile¿ programming resources, to reinforce their own development staff and take advantage of innovative approaches produced by ¿fresh minds¿ all over the world.
Schmitz, Patrice-Emmanuel
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