Results 151 to 160 of about 2,170,936 (313)
A supply side story for a threshold model: Endogenous growth of the free and open source community [PDF]
The study of social institutions producing and disseminating knowledge has mainly concentrated on two main concepts: Science and Technology. This paper examines a recent institutional form that seems not to resemble either of the other two; that is ...
F. Rullani, L. Zirulia
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Comparing Eight Parameter Estimation Methods for the Ratcliff Diffusion Model Using Free Software. [PDF]
Front Psychol, 2020 Alexandrowicz RW, Gula B.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Open SaaS: Using Free and Open Source Software as Software-as-a-Service
, 2015 Under German copyright law, rights of use cannot be granted for so-called unknown types of use. Software-as-a-Service (hereinafter: “SaaS”) is a use considered to be unknown until the mid 1990s.
Ballhausen, Miriam
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Factors and strategies based on free software that promote organizational learning in the technology area of ??the University of Nariño [PDF]
, 2018 Este trabajo de grado se enfoca en diseñar una estrategia basada en herramientas de software libre que favorezcan el aprendizaje organizacional en el Área de Tecnología de la Universidad de Nariño. Para cumplir este propósito, se identifican los factores
Arteaga Castillo, Edgard Andrés
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
GeoGebra: A reliable and free software for measuring acetabular cup anteversion on digitalized plain radiographs. [PDF]
J Clin Orthop Trauma, 2020 Bachhal V +4 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source