Results 41 to 50 of about 36,044 (265)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Million-Q free space meta-optical resonator at near-visible wavelengths

Nature Communications
High-quality (Q)-factor optical resonators with extreme temporal coherence are of both technological and fundamental importance in optical metrology, continuous-wave lasing, and semiconductor quantum optics.
Jie Fang, Rui Chen, David Sharp, Enrico M. Renzi, Arnab Manna, Abhinav Kala, Sander A. Mann, Kan Yao, Christopher Munley, Hannah Rarick, Andrew Tang, Sinabu Pumulo, Yuebing Zheng, Vinod M. Menon, Andrea Alù, Arka Majumdar   +15 more
doaj   +1 more source

Α dual‐hop equivalent structure of a generalised multi‐hop free‐space optics network

IET Communications, 2021
The performance of free‐space optics links strongly depends on scintillation effects caused by the atmospheric turbulence appearance. A widely adopted way to counterbalance the expected deterioration due to scintillation is to employ cooperative and ...
Nikolaos A. Androutsos, Hector E. Nistazakis, Harilaos G. Sandalidis, Erich Leitgeb, George S. Tombras   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Modulated Quasi-Continuous-Wave Laser Module for Free-Space Optics

Photonics
A quasi-continuous-wave (QCW) laser module based on a half-bridge structure is proposed for the low-voltage silicon photonics application, which forms a continuous-wave (CW) laser output when it equally distributes the heat dissipation into all lasers ...
Chun-Hao Chen, Chun-Hsiung Lin, Hao-Chung Kuo, Yu-Heng Hong, Ching-Yao Liu, Kai-En Lin, Yueh-Tsung Shieh, Shyr-Long Jeng, Edward-Yi Chang, Wei-Hua Chieng   +9 more
doaj   +1 more source

A high bit rate free space optics based ring topology having carrier‐less nodes

IET Communications, 2021
A free space optics based ring topology that transmits full‐duplex data to four different nodes in the ring is proposed. The link is designed such that the four nodes do not require a local optical source to transmit the uplink data.
Jawad Mirza, Waqas A. Imtiaz, Abdulah Jeza Aljohani, Salman Ghafoor   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source