Results 51 to 60 of about 36,044 (265)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The propagation of Hermite–Gauss wave packets in optics and quantum mechanics

Natural Sciences
The two‐dimensional paraxial equation of optics and the two‐dimensional time‐dependent Schrödinger equation, derived as approximations of the three‐dimensional Helmholtz equation and the three‐dimensional time‐independent Schrödinger equation ...
John S. Briggs
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Diffractive optical computing in free space

Nature Communications
AbstractStructured optical materials create new computing paradigms using photons, with transformative impact on various fields, including machine learning, computer vision, imaging, telecommunications, and sensing. This Perspective sheds light on the potential of free-space optical systems based on engineered surfaces for advancing optical computing ...
Jingtian Hu, Deniz Mengu, Dimitrios C. Tzarouchis, Brian Edwards, Nader Engheta, Aydogan Ozcan   +5 more
openaire   +3 more sources

Review on Free Space Optics [PDF]

INTERNATIONAL JOURNAL OF COMPUTERS & TECHNOLOGY, 2013
Present era demands high bandwidth with high data rates especially for internet. For high data rates requires high speed transmission medium like optical fiber. To overcome the bottle neck of last mile communication free space optics has emerged as a better option for radio engineers.
Er. Rajeev Thakur, Er. Sukhbir Singh, Er. Abhishek Sharma   +2 more
openaire   +1 more source

Controlling the Spatial Coherence of an Optical Source Using a Spatial Filter

Applied Sciences, 2018
This paper presents the theory for controlling the spectral degree of coherence via spatial filtering. Starting with a quasi-homogeneous partially coherent source, the cross-spectral density function of the field at the output of the spatial filter is ...
Milo W. Hyde
doaj   +1 more source

Quantum optics with Rydberg superatoms

Journal of Physics Communications, 2023
Quantum optics based on highly excited atoms, also known as Rydberg atoms, has cemented itself as a powerful platform for the manipulation of light at the few-photon level.
Jan Kumlin, Christoph Braun, Christoph Tresp, Nina Stiesdal, Sebastian Hofferberth, Asaf Paris-Mandoki   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Metamaterial unipolar quantum optoelectronics for mid-infrared free-space optics

APL Photonics
Free-space optical communications in the mid-infrared transparency windows (4–5 and 8–14 μm wavelength regions) is emerging as a viable solution for high bitrate data transmission.
T. Bonazzi, H. Dely, P. Didier, D. Gacemi, B. Fix, M. Beck, J. Faist, A. Harouri, I. Sagnes, F. Grillot, A. Vasanelli, C. Sirtori   +11 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source