Results 61 to 70 of about 4,513,547 (298)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Organizacja czasu wolnego i formy rekreacji w życiu współczesnej rodziny
In the article it was analized the use of free time and recreational time in the family, and the attention was devoted to the motivation to active recreational use of free time.
Michał Bąkowicz, Ewa Kotnis
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Study Regarding Rural Farm Services that Contribute to the Increasing of Free Time
The service structure that contribute to the increasing of free time in an agrotourist farm comprises a diverse range of activities, some of them with old t seniority, that have not undergone major changes, other recent or reinvented, for diversifying ...
Cornelia Petroman +5 more
doaj
Design of a Delayless Feedback Path Free 2nd-order Two-Path Time-Interleaved Discrete-Time Delta-Sigma Modulator- a New Approach [PDF]
This paper presents the design procedure for a 2nd_order two-path Discrete-Time Time-Interleaved (DTTI) ΔΣ modulator from a conventional single-loop 2nd-order Discrete-Time (DT) ΔΣ modulator through the use of time domain equations and time-interleaving ...
Talebzadeh, J., Kale, I.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A recent theory proposes that storing information in long-term memory depletes a limited resource which recovers gradually over time. Here, we provide a critical test of this theory by showing that free recall is worse if a word is preceded during study ...
Lynne Reder +2 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The article presents the results of a research that analyzes free time usage by lower class teenagers. The analysis on how teenagers manage their free time can supply data for the development of psychoeducative intervention and the promotion of this ...
Jorge Castellá Sarriera +3 more
doaj
Estudio de tipo descriptivo transversal y correlacional en que se analizan los hábitos de utilización del tiempo libre de los estudiantes de la Institución de Educación Superior Santo Tomás en Talca, de las carreras del área de la salud: Enfermería ...
MARTA LEMP PAREDES, VERONICA BEHN THEUNE
doaj +1 more source

