Results 81 to 90 of about 12,862,021 (286)
Psicologia: Reflexão e Crítica, 2007 The article presents the results of a research that analyzes free time usage by lower class teenagers. The analysis on how teenagers manage their free time can supply data for the development of psychoeducative intervention and the promotion of this ...
Jorge Castellá Sarriera +3 more
doaj
Ciencia y EnfermeríaEstudio de tipo descriptivo transversal y correlacional en que se analizan los hábitos de utilización del tiempo libre de los estudiantes de la Institución de Educación Superior Santo Tomás en Talca, de las carreras del área de la salud: Enfermería ...
MARTA LEMP PAREDES, VERONICA BEHN THEUNE
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Optimality conditions applied to free-time multi-burn optimal orbital transfers
, 2016 While the Pontryagin Maximum Principle can be used to calculate candidate extremals for optimal orbital transfer problems, these candidates cannot be guaranteed to be at least locally optimal unless sufficient optimality conditions are satisfied. In this
Chen, Zheng
core +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
We Must Do Better: It's Time to Make Alberta Poverty-Free [PDF]
, 2009 This report, authored by Jim Gurnett (in partnership with the ESPC, Public Interest Alberta, and the Bissell Centre), is a follow up to the We Can Do Better report released in 2009. We Must do Better overviews: the results of 5 poverty forums held across
Bill Moore-Kilgannon +2 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source