Results 91 to 100 of about 12,862,021 (286)
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2009 Bu araştırmanın temelini, Muğla il merkezinde çalışan devlet memurlarının boşzaman değerlendirme eğilimleri, Muğla ilinin bu amaca yönelik tesis ve faaliyet imkânları, geleceğe yönelik olmasıistenen tesis ve faaliyet istekleri ve boşzamanlarıfaal olarak ...
Selçuk Özdağ +4 more
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
CULTURE DURING THE TRANSITION PERIOD: REALITIES AND TENDENCIES [PDF]
Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2015 The present article represents the result of a national sociological research conducted in the rural communities of the Republic of Moldova and it is based on the analysis of the statistical yearbooks data, which describe the situation of cultural ...
CARAMAN IURIE
doaj
LEISURE TIME FOR YOUNG PEOPLE AND ADULTS [PDF]
Analele Universităţii din Craiova. Psihologie, PedagogieThis study highlights the interpretation given to leisure time and the changes that have brought us to the current understanding of leisure practices. The study begins with the evolution of the concept of leisure time and deals with various perspectives ...
Vali ILIE
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Ciencia y Enfermería, 2008 Estudio de tipo descriptivo transversal y correlacional en que se analizan los hábitos de utilización del tiempo libre de los estudiantes de la Institución de Educación Superior Santo Tomás en Talca, de las carreras del área de la salud: Enfermería ...
MARTA LEMP PAREDES, VERONICA BEHN THEUNE
doaj
Playing is sharing. La condivisione e il tempo libero nelle reti sociali di gioco
Archivio Antropologico Mediterraneo, 2019 To many people playing is a substantial part of their free time and has become an opportunity to create societal networks, spaces for participation, identity but also opportunities for consumption and sharing.
Aurelio Castro
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source