Results 111 to 120 of about 21,311,578 (293)

Significations sociales du temps libre et loisirs passifs des séniors

open access: yesRevue Internationale Animation, Territoires et Pratiques Socioculturelles
Cet article vise à comprendre les déterminants du choix des loisirs de type passif par les séniors de la Fédération des associations de fonctionnaires et agents de l’État à la retraite de Côte d’Ivoire, malgré les prescriptions en matière de mobilité des
Konan Jules Koffi   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

A comparative study between conventional and solids-free sewerage systems [PDF]

open access: yes, 2004
ThesisThe aim of this study was to examine the possibility of more suitable and economic alternatives to existing conventional sewerage reticulation systems where such systems might be required.
Grobbelaar, Nicolaas Josef
core  

THE ART OF LEADING FREE TIME. LEADERSHIP LESSONS IN RECREATION [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
Free time is a fundamental element in ensuring the balance between professional and personal life, being essential for both mental health and individual performance.
GUȚĂ EDUARD LEONARD
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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