Results 101 to 110 of about 12,862,021 (286)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Le « problème » de l’adolescence : le loisir contre le temps libre

open access: yesSociologies, 2011
Two reports are essential about teenager’s public policy of the leisure: on the one hand the devices of occupation of free time are legion and a plethora of contracts free time are subsidized by cities council and local governments; whereas a large range
Joël Zaffran
doaj  

Physical activity and other forms of spending free time by first-year nursing students depending on their age

open access: yesRozprawy Społeczne
The aim of the study was to assess the level of physical activity and other forms of spending free time among nursing students depending on the age of the respondents.
Agnieszka Dmitruk, Wojciech Hołub
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Relationship between free-time physical activity and sleep quality in Brazilian university students. [PDF]

open access: yesSci Rep, 2023
Santos M   +6 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Recreational activity of students from Preschool Teacher Training College in Sabac [PDF]

open access: yesSinteze, 2018
This article deals with free time and recreation of college students. The aim of this research is to establish how much free time students from Preschool Teacher Training College in Sabac have and how they use it, as well as how much they are engaged in ...
Pantić Zoran S., Stamatović Milovan V.
doaj  

Decision Time for Free Will [PDF]

open access: yesNeuron, 2011
In this issue of Neuron, Fried et al. report electrical recordings from single neurons in several areas of the human medial frontal lobe prior to voluntary movement. These data shed important new light on the neuronal mechanisms of human volition and on the hotly debated relation between consciousness and will.
openaire   +2 more sources

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