Results 131 to 140 of about 4,513,547 (298)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Real-time, open controller for reconfigurable manufacturing systems [PDF]

open access: yes, 2013
Thesis (M. Tech. (Information Technology)) -- Central University of technology, Free State, 2013Markets for manufactured products are characterized by a fragmentation of the market (with regards to size and time), and by shorter product cycles.
Tlale, Moretlo Celia
core  

Language politics and the struggle for the soul of the University of the Free State (UFS): A microcosm of the socio-political and economic struggles in the Free State Province through time

open access: yes, 2018
For the better part of the last century the University of the Free State (UFS) – as the “most prestigious” higher education institution in the province – has been a key site for institutional language politics in the province. This brand of institutional
Mwaniki, Munene
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Development of a rhino anti-poaching model for game farms and nature reserves in the Free State Province of South Africa [PDF]

open access: yes, 2018
Thesis (Doctor of Technology in Agriculture) -- Central University of Technology, Free State, 2018During the last ten years, the rhino populations of South Africa have suffered under an intense poaching onslaught.
Jordaan, H.L.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Some Problems of Political Socialization of the Youth in a Mirror of Empirical Research in a Mirror of Empirical Research

open access: yesУправленческое консультирование, 2018
In article some results of empirical sociological research of problems of political socialization of youth are discussed. Answers of respondents to questions of structure of actual interests and values are analyzed.
Ilija Viktorovich Strelnikov
doaj  

The reflection of language in culture and identity: A case of Basotho in the Free State Province and Lesotho. [PDF]

open access: yes, 2018
Published ThesisThe research investigates the relationship between language, culture and identity among the Basotho residing in the Free State Province of South Africa and Lesotho. The study attempts to reveal how each of the elements namely; language,
Mokuoane, Matsie Cassandra Ntsana
core  

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