Results 141 to 150 of about 4,952,966 (312)

FREE WILL HAS A NEURAL SUBSTRATE: CRITIQUE OF JOSEPH F. RYCHLAK'S DISCOVERING FREE WILL AND PERSONAL RESPONSIBILITY

open access: yesZygon, 1983
. Ably marshalling ideas from theology, philosophy, and neurology, personality theorist Joseph F. Rychlak criticizes mechanistic psychologists' neglect of will and responsibility; these human qualities involve dialectically considering alternatives.
doaj   +2 more sources

Yes, We Have Conscious Will [PDF]

open access: yes, 2007
In this paper I examine Daniel M. Wegner's line of argument against the causal efficacy of conscious will, as presented in Wegner's book "The Illusion of Conscious Will" (Cambridge, MA: The MIT Press, 2002).
Sharlow, Mark
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Complexity Theory, Quantum Mechanics and Radically Free Self Determination

open access: yes, 2001
It has been claimed that quantum mechanics, unlike classical mechanics, allows for free will. In this paper I articulate that claim and explain how a complex physical system possessing fractal-like self similarity could exhibit both self consciousness ...
Pestana, Mark Stephen
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Free Will According to the Gnostics

open access: yes, 2020
The Gnostic idea of free will is fundamentally different from the Greek philosophical one, firstly because every Gnostic doctrine is aimed to instruct about eschatological salvation and not just about the right way of living and being happy, secondly ...
Aldo Magris
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A framework for an affordable pricing strategy at the Central University of Technology, Free State [PDF]

open access: yes, 2011
Thesis (D. Tech. (Cost and Management Accounting)) -- Central University of Technology, Free State, 2011The focus area of this research project is on the pricing function in an organisation.
Smit, Louise Mancy
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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