Results 151 to 160 of about 12,878,813 (328)

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Free Will of an Ontologically Open Mind [PDF]

open access: yes
The problem of free will has persistently resisted a solution throughout centuries. There is reason to believe that new elements need to be introduced into the analysis in order to make progress.
Scheffel, Jan
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Free will, de Sam Harris

open access: yesGriot: Revista de Filosofia, 2015
Gabriel Garmendia da Trindade
doaj   +1 more source

Free Blood Corticoids in the Newborn Infant1 [PDF]

open access: bronze, 1954
Robert Klein   +2 more
openalex   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

The rationalist of Aquino: rescuing Aquinas from intellective determinism

open access: yesNordicum-Mediterraneum, 2006
Aquinas's theory of human action seems to reduce the will to the status of an obedient servant, who can only choose actions that intellect has judged approvingly. So how can Aquinas claim that the will is free? And can his theory account for our apparent
Sigurdur Kristinsson
doaj  

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