Results 51 to 60 of about 17,880,075 (308)
Special issue of EuJAP: Free Will and Epistemology
European Journal of Analytic Philosophy, 2020 Preface to the Special Issue on Free Will and Epistemology written by Robert ...
Robert Lockie +3 more
doaj
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Free will, temptation, and self-control: We must believe in free will. We have no choice (Isaac B. Singer). [PDF]
Baumeister, Sparks, Stillman, and Vohs (2007), sketch a theory of free will as the human ability to exert self-control. Self-control can produce goal-directed behavior, which free will conceptualized as random behavior cannot.
Vosgerau, J +2 more
core +2 more sources
Forum: Qualitative Social Research, 2005 Neuroscientists have reopened the longstanding question of whether human beings have free will. In this article, I analyze their claims to have experimentally falsified the existence of free will. In order to provide an existence proof for something, its
Uwe Laucken
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Accommodating Retrocausality with Free Will
Quanta, 2016 Retrocausal models of quantum mechanics add further weight to the conflict between causality and the possible existence of free will. We analyze a simple closed causal loop ensuing from the interaction between two systems with opposing thermodynamic ...
Yakir Aharonov +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Is Free Will Scepticism Self-Defeating?
European Journal of Analytic Philosophy, 2019 Free will sceptics deny the existence of free will, that is the command or control necessary for moral responsibility. Epicureans allege that this denial is somehow self-defeating.
Simon-Pierre Chevarie-Cossette
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Free Software without a Free Lunch or Free Beer [PDF]
IEEE Micro, 2018 Economists like to say that there are no free lunches. How does that attitude apply to free software and services?
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source