Results 21 to 30 of about 488,015 (266)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Comparison of clustering and phenotyping approaches for subclassification of type 2 diabetes and its association with remission in Indian population

open access: yesScientific Reports
Identification of novel subgroups of type 2 diabetes (T2D) has helped improve its management. Most classification techniques focus on clustering or subphenotyping but not on both. This study aimed to compare both these methods and examine the rate of T2D
Pramod Tripathi   +8 more
doaj   +1 more source

Intellectual Property Rights in Traditional Knowledge: Enabler of Sustainable Development

open access: yesUtrecht Journal of International and European Law, 2016
Traditional knowledge (TK) plays an integral role in supporting sustainable development practices, and can act as an enabler of sustainable development in indigenous and local communities (ILCs) through recognition of intellectual property rights (IPRs).
Freedom-Kai Phillips
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Baseline clinical and biochemical profiles of type 2 diabetes patients enrolled in a lifestyle management program in India, a cross-sectional study

open access: yesScientific Reports
Assessing the clinical and biochemical profiles of patients with type-2 diabetes (T2D) is vital for understanding the disease characteristics and improving disease management.
Pramod Tripathi   +7 more
doaj   +1 more source

Orom Sasadu: Hakikat dan Maknanya Bagi Masyarakat Suku Sahu Di Halmahera Barat, Maluku Utara

open access: yesJurnal Filsafat, 2019
Indonesia has a variety of dining customs. Traditions that can be mentioned, among others Makan Patita in Ambon, Makan Basamo in Padang, Megibung in Bali, Bancakan in Bandung, and Orom Sasadu in Sahu, West Halmahera. This paper aimes to raise the meaning
Ricardo Freedom Nanuru
doaj   +1 more source

Pocket hematoma after pacemaker or defibrillator surgery: Direct oral anticoagulants versus vitamin K antagonists

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2022
Background: Direct oral anticoagulants (DOACs) are the preferred choice of oral anticoagulation in patients with atrial fibrillation (AF). Randomized trials have demonstrated the efficacy and safety of DOAC in patients undergoing a cardiac implantable ...
John de Heide   +9 more
doaj   +1 more source

ARTISTIC FREEDOM AND ACADEMIC FREEDOM

open access: yesLaw and Contemporary Problems, 1990
The Cincinnati, Ohio, jury surely did the right thing by rejecting obscenity charges against Contemporary Arts Center Director Dennis Barrie following the exhibition of Robert Mapplethorpe's photographs.' Yet a different outcome at that trial might have forced higher courts to consider to what degree the fine arts enjoy protection under the first ...
openaire   +2 more sources

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

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