Results 21 to 30 of about 628,084 (317)

Psychometric validation of type 2 Diabetes Distress Assessment System in an Indian type 2 diabetes population

Scientific Reports
Diabetes distress (DD) significantly burdens and negatively impacts self-management and health outcomes in patients with type 2 diabetes (T2D). Early detection and management of DD are crucial for effective T2D management.
Baby Sharma, Pramod Tripathi, Nidhi Kadam, Diptika Tiwari, Anagha Vyawahare, Thejas Kathrikolly, Malhar Ganla   +6 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Comparison of clustering and phenotyping approaches for subclassification of type 2 diabetes and its association with remission in Indian population

Scientific Reports
Identification of novel subgroups of type 2 diabetes (T2D) has helped improve its management. Most classification techniques focus on clustering or subphenotyping but not on both. This study aimed to compare both these methods and examine the rate of T2D
Pramod Tripathi, Anagha Vyawahare, Nidhi Kadam, Diptika Tiwari, Mayurika Das Biswas, Thejas Kathrikolly, Baby Sharma, Venugopal Vijayakumar, Maheshkumar Kuppusamy   +8 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Baseline clinical and biochemical profiles of type 2 diabetes patients enrolled in a lifestyle management program in India, a cross-sectional study

Scientific Reports
Assessing the clinical and biochemical profiles of patients with type-2 diabetes (T2D) is vital for understanding the disease characteristics and improving disease management.
Pramod Tripathi, Nidhi Kadam, Thejas Kathrikolly, Diptika Tiwari, Anagha Vyawahare, Baby Sharma, Malhar Ganla, Banshi Saboo   +7 more
doaj   +1 more source

Orom Sasadu: Hakikat dan Maknanya Bagi Masyarakat Suku Sahu Di Halmahera Barat, Maluku Utara

Jurnal Filsafat, 2019
Indonesia has a variety of dining customs. Traditions that can be mentioned, among others Makan Patita in Ambon, Makan Basamo in Padang, Megibung in Bali, Bancakan in Bandung, and Orom Sasadu in Sahu, West Halmahera. This paper aimes to raise the meaning
Ricardo Freedom Nanuru
doaj   +1 more source

Pocket hematoma after pacemaker or defibrillator surgery: Direct oral anticoagulants versus vitamin K antagonists

International Journal of Cardiology: Heart & Vasculature, 2022
Background: Direct oral anticoagulants (DOACs) are the preferred choice of oral anticoagulation in patients with atrial fibrillation (AF). Randomized trials have demonstrated the efficacy and safety of DOAC in patients undergoing a cardiac implantable ...
John de Heide, Marisa van der Graaf, Marijn J. Holl, Rohit E. Bhagwandien, Dominic A.M.J. Theuns, André de Wit, Felix Zijlstra, Tamas Szili-Torok, Mattie J. Lenzen, Sing-Chien Yap   +9 more
doaj   +1 more source

ARTISTIC FREEDOM AND ACADEMIC FREEDOM

Law and Contemporary Problems, 1990
The Cincinnati, Ohio, jury surely did the right thing by rejecting obscenity charges against Contemporary Arts Center Director Dennis Barrie following the exhibition of Robert Mapplethorpe's photographs.' Yet a different outcome at that trial might have forced higher courts to consider to what degree the fine arts enjoy protection under the first ...
openaire   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source