Results 141 to 150 of about 115,173 (332)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Exploring Freelance Journalism in the Emirati Media Ecosystem: A Comparison of Using Freelancers Among National Media Organizations and Their Voluntary Professional Autonomy

open access: yesJournalism and Media
What are the nature and characteristics of freelance journalism in the UAE media system? To answer the main research paper question, this study investigates the usage and influence of freelancers in the Emirati media ecosystem through a comparison among ...
Fatima Ahmed Alawadhi   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Is the future freelance? [PDF]

open access: yes, 2008
Does new media signal the end of a steady job? Budding multi-skilled BBC video journalist Angela Saini thinks so.
Beckett, Charlie
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

AdS3 freelance holography: a detailed analysis

open access: yesJournal of High Energy Physics
Freelance holography program is an extension of the gauge/gravity correspondence in which the boundary theory can reside on any timelike codimension-one surface in AdS space, and the boundary conditions on the bulk fields can be chosen arbitrarily ...
M. M. Sheikh-Jabbari, V. Taghiloo
doaj   +1 more source

Nurturing enterprise in work-based learning [PDF]

open access: yes, 2011
Laura wrote a Chapter called Nurturing Enterprise in Work Based Learning – this work brings together case studies and research that she has conducted into Work Based Learning and packages it for a wider audience, with a specific aim of informing ...
Taylor, L
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Science and the media: securing the future [PDF]

open access: yes, 2010
A report by the Science and the Media Expert Group, in which actions and recommendations are made which are aimed at delivering changes to improve the quality of science in the media and also stimulate an important debate about the future of science ...

core  

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