Results 191 to 200 of about 22,508 (244)

Lower trust in artificial intelligence than physicians coexists with high willingness to engage in artificial intelligence-assisted prostate cancer management among active surveillance patients. [PDF]

BJUI Compass
Chai ES, Abraham K, Hanes R, Williams A, Wolinsky H, Kryvenko ON, Stoyanova R, Penedo FJ, Khandekar A, Nahar B, Gonzalgo ML, Parekh DJ, Punnen S.   +12 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Household Exposure to Secondhand and Thirdhand Smoke and Associated Factors Among Preschool-Aged Children - Beijing Municipality, China, 2023. [PDF]

China CDC Wkly
Cao Y, Meng Y, Xu L, Shi J, Dong J, Xiao L, Wang Y.   +6 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Time perspective status and associated factors among young and middle-aged women with gynecologic malignancies who have parenting responsibilities. [PDF]

Asia Pac J Oncol Nurs
Ma G, Deng C, Ding Q, Gu C, Peng J.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

He Cracked Malaria's Genome in Mali. Now He's Advising the UN. [PDF]

ACS Cent Sci
Lillian S.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Depression and anxiety before and after bariatric surgery: a longitudinal cohort study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. [PDF]

Front Psychiatry
Alhujaili NA, Alsulami SS, Almutairi WA, Al-Khalawi E, Sabbahi A, Alghamdi AA, Aljiffry M.   +6 more
europepmc   +1 more source