Results 101 to 110 of about 26,374 (286)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

“Knowing Me, Knowing You” the Importance of Networking for Freelancers’ Careers: Examining the Mediating Role of Need for Relatedness Fulfillment and Employability-Enhancing Competencies

Frontiers in Psychology, 2019
Research has shown the importance of engaging in networking behaviors for employees’ career success. Networking behaviors can be seen as a proactive way of creating access to career-related social resources and we argue that this type of proactive career
Sofie Jacobs, Sofie Jacobs, Ans De Vos, Ans De Vos, David Stuer, David Stuer, Beatrice I. J. M. Van der Heijden, Beatrice I. J. M. Van der Heijden, Beatrice I. J. M. Van der Heijden, Beatrice I. J. M. Van der Heijden, Beatrice I. J. M. Van der Heijden   +10 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Re-articulating Autonomy and Solidarity. The Case of Smart: The Largest European Network of Freelance Cooperatives

Partecipazione e Conflitto
This article explores how workers' autonomy is supported by Smart, the largest network of freelance cooperatives in Europe. Based primarily on ethnographic data, we argue that this case shows that workers' autonomy is not necessarily linked to being self-
Mathilde Mondon-Navazo, Annalisa Murgia, Sarah de Heusch   +2 more
doaj   +1 more source

Organization of the News Industry, The Case of 'Making-or-Buying' Article s [PDF]

In this paper the two canonical theories of the firm - transaction costs economics and the knowledge-based view of the firm - predictions on 'make-or-buy' are tested on the news industry.
Jan Vang
core  

Evidence-Based Design: Theoretical and Practical Reflections of an Emerging Approach in Office Architecture [PDF]

, 2009
Evidence-based design is a practice that has emerged only relatively recently, inspired by a growing popularity of evidence-based approaches in other professions such as medicine.
Budgen, Andrew, Lonsdale, Nathan, Penn, Alan, Sailer, Kerstin, Turner, Alasdair   +4 more
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Social well-being of freelancers in Russia [PDF]

, 2016
Статья посвящена анализу социального самочувствия фрилансеров в современном российском обществе. Социальное самочувствие фрилансеров связано с ценностями, представлениями об успехе и удовлетворенностью различными аспектами жизнедеятельности.
Kharchenko, V. S., Харченко, В. С.   +1 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Income Taxes and Entrepreneurial Choice: Empirical Evidence from Germany [PDF]

Entrepreneurial activity is often regarded as an engine for economic growth and job creation. Through tax policy, governments possess a potential lever to influence the decisions of economic agents to start and close small businesses. In Germany, the top
Frank M. Fossen, Viktor Steiner
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