Results 111 to 120 of about 26,374 (286)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Building Imaginary Worlds (2012) by Mark J.P. Wolf and Revisiting Imaginary World (2016) edited by Mark J.P. Wolf [PDF]
, 2017 Book review of Building Imaginary Worlds (2012) by Mark J.P. Wolf and Revisiting Imaginary Worlds (2016), edited by Mark J.P.
Higgins, Andrew
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Self-employment in Germany and the UK: Labor market regulation, risk-management and gender in comparative perspective [PDF]
Within the wide range of new forms of work self-employment seems to be a distinct feature concerning a growing part of the male and female labor force in industry and services in both Germany and the UK.
Gottschall, Karin, Kroos, Daniela
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Astroserver - Research Services in the Stellar Webshop
, 2017 A quick look at research and development in astronomy shows that we live in exciting times. Exoplanetary systems, supernovae, and merging binary black holes were far out of reach for observers two decades ago and now such phenomena are recorded routinely.
Nemeth, Peter
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
"SQUID GAME": HUMAN IN THE WORLD OF CONTEMPORARY CAPITALISM
Вісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетіїCinema as an art form developed rapidly in the last century and has not lose its position in the 21st century. What we see on the screen is the embodiment of thoughts, actions, stories of people and society.
Sergey Manukyan
doaj +1 more source
Commitment freier Mitarbeiter: Erscheinungsformen und Einflussmöglichkeiten am Beispiel von IT-Freelancern [PDF]
, 2006 Seit Jahren ist die Tendenz zu erkennen, dass Arbeitsverhältnisse flexibler gestaltet werden. Bislang wenig erforscht ist, was das für Loyalität und Commitment der flexibel beschäftigten Mitarbeiter bedeutet.
Süß, Stefan
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source