Results 141 to 150 of about 14,676 (335)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Cultural Freelancers Study 2024 [PDF]

This Arts Council England (ACE) commissioned report is based on a study of freelance workers in the creative and cultural sector in England. It documents the current challenges and opportunities experienced by creative and cultural practitioners in ...
Maples, Holly, Klich, Rosemary, Hancock, Philip, Tyler, Melissa   +3 more
core  

Re-articulating Autonomy and Solidarity. The Case of Smart: The Largest European Network of Freelance Cooperatives

Partecipazione e Conflitto
This article explores how workers' autonomy is supported by Smart, the largest network of freelance cooperatives in Europe. Based primarily on ethnographic data, we argue that this case shows that workers' autonomy is not necessarily linked to being self-
Mathilde Mondon-Navazo, Annalisa Murgia, Sarah de Heusch   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A Review on Freelancing Platforms and Client-Freelancer Systems

The rapid growth of the digital economy has significantly increased the demand for freelancing platforms that connect clients with skilled professionals. This review paper analyzes various existing freelancing systems and platforms, focusing on, their features, methodologies, and limitations.
Sabale, Dr. Amar V., Jayade, Siddhi Sagar, Raut, Khushi Sharad, Ugale, Tejashree Satish, Bawane, Bhumika Vijay, Dhonde, Khushi Santosh   +5 more
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Making it work: Connecting freelancers with local government [PDF]

This policy brief is for creative freelancers seeking local government-funded opportunities and ...
May, Will, Ashton, Daniel, Jahan, Aiysha
core   +1 more source

"SQUID GAME": HUMAN IN THE WORLD OF CONTEMPORARY CAPITALISM

Вісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетії
Cinema as an art form developed rapidly in the last century and has not lose its position in the 21st century. What we see on the screen is the embodiment of thoughts, actions, stories of people and society.
Sergey Manukyan
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source