Results 141 to 150 of about 36,439 (343)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Atypical working practices in the East Midlands [PDF]
The aim of this research was to examine the extent and nature of atypical working practices in the East Midlands region and, in particular, look at the way in which these forms of work are likely to encourage employment and economic development in remote
Experian
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
"SQUID GAME": HUMAN IN THE WORLD OF CONTEMPORARY CAPITALISM
Cinema as an art form developed rapidly in the last century and has not lose its position in the 21st century. What we see on the screen is the embodiment of thoughts, actions, stories of people and society.
Sergey Manukyan
doaj +1 more source
Building Imaginary Worlds (2012) by Mark J.P. Wolf and Revisiting Imaginary World (2016) edited by Mark J.P. Wolf [PDF]
Book review of Building Imaginary Worlds (2012) by Mark J.P. Wolf and Revisiting Imaginary Worlds (2016), edited by Mark J.P.
Higgins, Andrew
core +2 more sources
Astroserver - Research Services in the Stellar Webshop
A quick look at research and development in astronomy shows that we live in exciting times. Exoplanetary systems, supernovae, and merging binary black holes were far out of reach for observers two decades ago and now such phenomena are recorded routinely.
Nemeth, Peter
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Income Taxes and Entrepreneurial Choice: Empirical Evidence from Germany [PDF]
Entrepreneurial activity is often regarded as an engine for economic growth and job creation. Through tax policy, governments possess a potential lever to influence the decisions of economic agents to start and close small businesses. In Germany, the top
Frank M. Fossen, Viktor Steiner
core

