Results 181 to 190 of about 14,676 (335)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Binden en boeien van freelancers

Dit onderzoek richt zich op het vergroten van de betrokkenheid van freelance projectmanagers bij WOP EVENTS B.V. In een arbeidsmarkt waarin flexibiliteit essentieel is, is het begrijpen van de motivatie van freelancers strategisch belangrijk. Aan de hand
van Zelst, Ron
core  

Isolation Of The Czech Online Marketing Freelancers

, 2018
Izolace, resp. izolovaný způsob práce freelancerů, je hlavní specifikum freelancingu, které ho odlišuje od podnikání a dalších typů pracovních vztahů.
Popovičová, Jasmína
core  

Editorial: Digital transformations and the changing nature of work. [PDF]

Front Sociol
Cruz SA, Soeiro J.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Introduction of Generative AI in Digital Platforms: Mental Health and Emotional Well-being of Freelancers

Generative AI (GenAI) has been a groundbreaking technological turning point for digital platforms and has marked a paradigm shift in global professional landscapes, with freelancers being at the forefront of these technological transformations.
Rahman, Md. Tuhinur, Salam, A. F.
core   +1 more source

Latent profiles analysis of Traditional Chinese Medicine Health Literacy in middle-aged and older adult patients with chronic diseases and its association with disease burden and self management. [PDF]

Front Public Health
Han G, Yang W, Wang J, Deng J, Shi T, Zhong Y, Zhang H.   +6 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Association between working hours, income, and work-related injury among freelancers in Japan: a cross-sectional study. [PDF]

J Occup Health
Watanabe K, Yokoyama K, Tsutsumi A.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source