Freeze-thaw strength regulates carbon density through microbial assembly processes and network clustering. [PDF]
Chen S +4 more
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Effect of Freeze-Thaw Cycle Times on Basic Properties and Bond Performance with Steel Reinforcement of Tunnel Lining Concrete in the Tibetan Plateau. [PDF]
Zang Y +6 more
europepmc +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Effects of Freeze-Thaw Cycles and Basalt Fiber Reinforcement on the Mechanical Properties and Constitutive Model of Lunar Regolith Simulant Geopolymer Under In Situ Construction Environments. [PDF]
Zhan J +5 more
europepmc +1 more source
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Study on the Freeze-Thaw Durability and Carbon Emission Reduction Benefits of Geopolymer EPS Concrete. [PDF]
Jian X +9 more
europepmc +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
No ...
openaire +2 more sources
Study on the Freezing Protection Effect of Melatonin on <i>Lactobacillus plantarum</i> FQR. [PDF]
Feng Y +5 more
europepmc +1 more source

