Results 71 to 80 of about 331,710 (264)

Relativistic freeze-in

Physics Letters B, 2019
We study production of scalar dark matter via the freeze--in mechanism in the relativistic regime, focussing on the simplest Higgs portal model. We derive the corresponding relativistic reaction rates based on the Bose--Einstein statistics taking into account the thermal mass effects as well as the change in the Higgs degrees of freedom at the ...
Lebedev, Oleg, Toma, Takashi
openaire   +4 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Interdecadal Changes in the Freeze Depth and Period of Frozen Soil on the Three Rivers Source Region in China from 1960 to 2014

Advances in Meteorology, 2017
On the basis of observed soil freeze depth data from 14 meteorological stations on the Three Rivers Source Region (TRSR) in China during 1960 to 2014, trends in the freeze depth, first date, last date, and duration of frozen soil were analyzed, together ...
Siqiong Luo, Xuewei Fang, Shihua Lyu, Qi Jiang, Jingyuan Wang   +4 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Frozen Ground Induces Seawater Retreat in Coastal Unconfined Aquifers

Geophysical Research Letters
While seawater intrusion (SWI) in coastal aquifers has been extensively investigated, most studies focused on unfrozen conditions. In many cold regions, frozen ground is common, yet its impact on SWI remains poorly understood.
Xiayang Yu, Yue Li, Li Pu, Junjie Wu, Pei Xin   +4 more
doaj   +1 more source

Correction: Freeze et al. The Bat Signal: An Ultraviolet Light Lure to Increase Acoustic Detection of Bats. Animals 2025, 15, 2458

Animals
In the original publication [...]
Samuel R. Freeze, Sabrina M. Deeley, Amber S. Litterer, J. Mark Freeze, W. Mark Ford   +4 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Melting and Freezing*

Nature, 1964
info:eu-repo/semantics ...
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source