Results 111 to 120 of about 2,998 (248)

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

Experimental study on dynamic mechanical properties and damage mechanisms models of concrete under freeze-thaw cycles. [PDF]

Sci Rep
Cao Y, Zhou J, Shao Y, Ye W, Wang H, Hua X, Bian H, Jin H.   +7 more
europepmc   +1 more source

Freeze Fracturing (Freeze-Fracture-Replication Method/Quick-Freeze Deep-Etching and Replica Labeling)

Denshi kenbikyo, 2000
Fujimoto, Kazushi, Tonosaki, Akira, Washioka, Hiroshi   +2 more
openaire   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Micro-CT Three-Dimensional Digital Modeling and Seepage Simulation of Coal under Liquid Nitrogen Fracturing. [PDF]

ACS Omega
Qiao Y, Wang L, Gan M, Li H, Zhang J, Zhang K, Wang H.   +6 more
europepmc   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

Advanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali, Zeeshan Alam Ansari, Reynaldo Carlos Kuizon Montalbo, Hailemichael Ayalew, Yu‐Sheng Hsiao, Chih‐Wei Chu, Hsiao‐hua Yu, Hsiung‐Lin Tu   +7 more
wiley   +1 more source

Study on the Dispersion Characteristics of Coal Complex Resistivity under the Effect of Liquid Nitrogen Cyclic Freeze-Thaw and Evaluation of Permeability Enhancement. [PDF]

ACS Omega
Li J, Xu X, Zhang Y, Zhang H, Hou H, Tian L, Jian K, Xue Z, Zhang Z.   +8 more
europepmc   +1 more source

Freeze Fracture Method

Japanese Journal of National Medical Services, 1975
ASAMOTO, Hitoshi, FURUTA, Mutsuhiro
openaire   +1 more source

Anisotropic Nanofiber Architectures for Strain‐Insensitive Pressure Sensing and Stretchable Interconnects

Advanced Electronic Materials, EarlyView.
Electrospun PEDOT/PAAm nanofiber mats exhibit anisotropic electromechanical behavior, maintaining stable resistance under tensile strain while showing pressure‐responsive resistance modulation under vertical loading. This direction‐dependent response highlights their potential as tensile‐stable, pressure‐responsive components for deformable sensing and
Seung‐Hyun Oh, Hyunmin Park, Guhyeon Kwon, Young‐Chang Joo, So‐Yeon Lee   +4 more
wiley   +1 more source

An ambient acoustic ice-fracturing dataset taken in shallow freshwater. [PDF]

Sci Data
Case J, Barnard A, Brown D.
europepmc   +1 more source