Results 161 to 170 of about 167,453,479 (294)

Selective γ8 transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor regulatory protein negative allosteric modulators: Efficacy in preclinical antiseizure models

Epilepsia, EarlyView.
Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta, Brock T. Shireman, Laurie P. Volak, Michael P. Maher, Michael K. Ameriks, David Bredt   +5 more
wiley   +1 more source

Frequency-Specific EEG burst dynamics in Parkinson's Disease and freezing of gait. [PDF]

J Neurol
Leedom M, Pallab MRA, Bharmauria V, Flouty O, Stuart S, Mancini M, Singh A.   +6 more
europepmc   +1 more source

From hydrogels to eutectogels: Emerging platforms for stretchable electronics

FlexMat, EarlyView.
The transition of wearable electronics toward long‐term reliability requires materials that resist dehydration without sacrificing tissue‐like softness and ionic conductivity. Eutectogels fulfill these demands by immobilizing deep eutectic solvents within tailored polymer networks.
Chang Zhou, Jiancheng Dong, Jiayu Hou, Shiyin Lin, Xingyu Liu, Hao Qiu, Mengting Zheng, Yuduo Zhang, Haijun Zhu, Kangjia Geng, Yidong Peng, Haoran Liu, Xu Zhang, Yunpeng Huang, Tianxi Liu   +14 more
wiley   +1 more source

What is new in Freezing of Gait? [PDF]

J Neurol
Gülke E, Lewis SJG.
europepmc   +1 more source

Engineering an artificial trachea: Quantitative benchmarks and modular strategies for mechanics, epithelialization, and vascular integration

FlexMat, EarlyView.
In this work, we first examine the limitations of surgical repair and stenting, including migration, granulation, mucus plugging, and infection. We then translate these failures into engineering constraints involving geometry, mechanics, fixation, degradation, junctional stress, and remodeling.
Yiwei Xu, Hanqing Dai, Qianwang Ye, Wanlu Zhang, Na Wang, Lei Xiong, Ruiqian Guo   +6 more
wiley   +1 more source

Freezing of Gait: A Tribute to Nir Giladi. [PDF]

Eur J Neurosci
Dos Santos de Oliveira L, Nucci MP, Silva-Batista C, Ribeiro de Souza C, de Lima-Pardini AC, Barbieri FA, Coelho DB.   +6 more
europepmc   +1 more source

Aerogel Fiber: A One‐Dimensional Programmable Porous Matter for Next Thermal Management Materials

Interdisciplinary Materials, EarlyView.
Aerogel fibers are redefined as one‐dimensional programmable porous matter, where thermal transport is governed by multiscale pathway engineering. By reconstructing and decoupling transport pathways from molecular to textile scales, these systems integrate insulation, radiative cooling, and adaptive thermal regulation.
Lizhi Ren, Zihui Liang, Xiangzhe Li, Huimin Wu, Sixing Xiong, Jin Qian, Kai Wang   +6 more
wiley   +1 more source

Towards the Prevention of Freezing of Gait in Parkinson's Disease. [PDF]

Eur J Neurosci
Tosserams A, Nonnekes J, Bloem BR, Postma EM.   +3 more
europepmc   +1 more source

Gut microbiota dysbiosis‐mediated gut NLRP3 inflammasome activation exacerbates corticospinal tract injury after intracerebral hemorrhage

Interdisciplinary Medicine, EarlyView.
Schematic depicting a gut‐brain pathway that exacerbates CST injury after ICH. Gut Microbiota Dysbiosis‐Mediated Gut NLRP3 Inflammasome Activation Exacerbates Corticospinal Tract Injury After Intracerebral Hemorrhage. Abstract Intracerebral hemorrhage (ICH) causes severe neurological deficits largely attributable to corticospinal tract (CST) injury ...
Meiqin Zeng, Meichang Peng, Chen He, Yanmeng Zhao, Zizhang Cheng, Mengchen Yu, Hao Tian, Lu Zhang, Wen Yuan, Qing Zeng, Jiandong Huang, Haitao Sun   +11 more
wiley   +1 more source

Model-based 3D gait biometrics

, 2013
Gait biometrics has attracted increasing interest in the computer vision and machine learning communities because of its unique advantages for recognition at distance. However, there have as yet been few gait biometric approaches which use temporal three-
Ariyanto, Gunawan
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