Results 171 to 180 of about 29,377 (308)
Abstract Artificial intelligence and automation are no longer just buzzwords in the biopharmaceutical industry. The manufacturing of a class of biologics, comprising monoclonal antibodies, cell therapies, and gene therapies, is far more complex than that of traditional small molecule drugs.
Shyam Panjwani, Hao Wei, John Mason
wiley +1 more source
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh +12 more
wiley +1 more source
This paper explores global solar PV deployment, cost trends, and grid integration challenges in 2025. It examines the role of energy storage in firming solar output and supporting electric vehicle (EV) growth, alongside policy shifts, investment flows, and technological innovations.
Ehsan Rezaee, S. Ravi P. Silva
wiley +1 more source
Fish Scales: A Multifunctional Biomaterial from Nature
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source
Freezing of Gait in Extrapontine Myelinolysis [PDF]
Jongmin Song +7 more
openaire +1 more source
ABSTRACT Bitter melon polysaccharides (BMPs), a key bioactive component of bitter melon, exhibit a range of biological activities including gut microbiota regulation, immune modulation, and antioxidant activity. Based on previous evidence of its protective effect on the colonic mucus barrier under high‐fat‐diet condition, this study evaluated the ...
Tangying Kang +6 more
wiley +1 more source
Technology for measuring freezing of gait
This report summarizes the existing literature on the use of technology for the assessment of freezing of gait (FOG) as well as the use of technology to provide insights into the mechanisms of FOG in people with Parkinson's disease. Specifically, this work was carried out for the 3rd International Workshop on Freezing of Gait in Jerusalem in 2023. This
Mancini, Martina +11 more
openaire +1 more source
Abstract This article examines how mobility restrictions imposed by governments during the COVID‐19 pandemic intensified reproductive and mobility injustices. It traces shifting configurations of privilege and inequality within marginalized groups whose reproductive desires remain legally and socially unrecognized.
Sara L. Friedman
wiley +1 more source
Electronic jelly: Engineering the mechanics of hydrogels for flexible electronics
By unifying mechanical reinforcement strategies—double networks, structural ordering, and dynamic interactions—this review demonstrates how engineered hydrogels can transcend their fragility to achieve the strength, toughness, and reliability required for flexible electronics, including wearable sensors, energy devices, and soft robotic systems ...
Tianfu Zheng +2 more
wiley +1 more source

