Results 211 to 220 of about 29,587 (307)

POLG‐Related Parkinsonism with Good Response to Deep Brain Stimulation

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Evdokia Efthymiou   +4 more
wiley   +1 more source

Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation

open access: yesMovement Disorders, EarlyView.
Abstract Adaptive deep brain stimulation (aDBS) represents an important evolution in the treatment of Parkinson's disease (PD), building on conventional DBS (cDBS) by adjusting stimulation in response to real‐time physiological signals. By enabling dynamic targeting of disease‐related neural activity, aDBS offers the potential for more precise ...
Thomas Koeglsperger   +5 more
wiley   +1 more source

Biomarkers of Leucine‐Rich Repeat Kinase 2 (LRRK2) and Lysosomal Dysfunction in Progressive Supranuclear Palsy

open access: yesMovement Disorders, EarlyView.
Abstract Background Common and rare genetic variants in leucine‐rich repeat kinase 2 (LRRK2) have been linked with sporadic and familial Parkinson's disease (PD). Recently, we discovered that common genetic variation near the LRRK2 locus determined survival in progressive supranuclear palsy (PSP).
Louise‐Kristine Nielsen   +27 more
wiley   +1 more source

Unilateral Freezing of Gait in Normal Pressure Hydrocephalus after Stroke

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Jose Portales   +2 more
wiley   +1 more source

Ex Vivo LRRK2 Activation in Asian G2385R and R1628P Variant Carriers and Idiopathic Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Leucine‐rich repeat kinase 2 (LRRK2) kinase inhibition is a promising therapeutic strategy for Parkinson's disease (PD), but the functional impact of Asian‐prevalent LRRK2 p.G2385R and p.R1628P variants remains unclear. Robust patient stratification and target engagement markers are needed for global LRRK2‐targeted trials ...
Tzi Shin Toh   +17 more
wiley   +1 more source

Accelerated Split‐Belt Gait Adaptation in Patients with Functional Tremor: Clues to a Generalized Precipitating Trait?

open access: yesMovement Disorders, EarlyView.
Abstract Background Functional neurological disorders (FNDs) are common, disabling conditions that are genuinely experienced and arise from functional rather than structural abnormalities. Although theoretical frameworks implicate aberrant integration of prior expectations and sensory input, empirical evidence is limited, and it remains unclear whether
Jorik Nonnekes   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy