Results 41 to 50 of about 167,453,479 (294)

Unveiling the Unpredictable in Parkinson’s Disease: Sensor-Based Monitoring of Dyskinesias and Freezing of Gait in Daily Life

Bioengineering
Background: Dyskinesias and freezing of gait are episodic disorders in Parkinson’s disease, characterized by a fluctuating and unpredictable nature. This cross-sectional study aims to objectively monitor Parkinsonian patients experiencing dyskinesias and/
Alessandro Zampogna, Luigi Borzì, Domiziana Rinaldi, Carlo Alberto Artusi, Gabriele Imbalzano, Martina Patera, Leonardo Lopiano, Francesco Pontieri, Gabriella Olmo, Antonio Suppa   +9 more
doaj   +1 more source

A new phenotype of choreic syndrome associating severe freezing of gait and chorea

Clinical Case Reports, 2020
The early onset of gait akinesia should not rule out the diagnosis of hereditary chorea. It would be helpful to proceed to a whole‐genome and long‐read sequencing in order to track a new pathogenic variant including noncoding repeat expansion.
Brice Laurens, Claire Delleci, Cyril Goizet, Umberto Spampinato, Pierre Burbaud, Etienne Guillaud, Emma Bestaven, Dominique Guehl   +7 more
doaj   +1 more source

Gait Initiation Impairment in Patients with Parkinson’s Disease and Freezing of Gait

Bioengineering, 2022
Freezing of gait (FOG) is a sudden episodic inability to produce effective stepping despite the intention to walk. It typically occurs during gait initiation (GI) or modulation and may lead to falls. We studied the anticipatory postural adjustments (imbalance, unloading, and stepping phase) at GI in 23 patients with Parkinson’s disease (PD) and FOG ...
Chiara Palmisano, Laura Beccaria, Stefan Haufe, Jens Volkmann, Gianni Pezzoli, Ioannis U. Isaias   +5 more
openaire   +4 more sources

Vibration stimulation to the lower limbs improves freezing of gait and modifies cortical electrical activities in Parkinson's disease

Neurotherapeutics
Muscle vibration, a form of proprioceptive stimulation, is a promising therapeutic method for alleviating freezing of gait in Parkinson's disease. This study aimed to investigate whether vibration stimulation enhances freezing of gait in Parkinson's ...
Puyuan Wen, Hong Zhu, Amin Chang, Xianwen Chen   +3 more
doaj   +1 more source

Wearable device intended for detection of fog episodes in Parkinson´s disease

Visión Electrónica, 2019
The episodes of Freezing of Gait (FOG) are a recurring symptom in people suffering from advanced stages of Parkinson's disease (PD). These are severe occurrences because they may cause falls to the patients, generating further traumas and concussions. In
Laura Carolina Rozo Hoyos, Juan Pablo Pulgarín González, Paula Andrea Morales Fandiño, Jonathan Gallego Londoño   +3 more
doaj   +1 more source

Structural magnetic resonance imaging in Parkinson disease with freezing of gait: A systematic review of literature [PDF]

OBJECTIVE: This review aims to the existing structural neuroimaging literature in Parkinson disease presenting with freezing of gait. The summary of this article provides an opportunity for a better understanding of the structural findings of freezing ...
Dewi Setyaning Bastiana, -, Muhammad Hamdan, Muhammad, Anggraini Dwi Sensusiati, -, Ade Pambayu Suharto, -   +3 more
core   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Translation, Cultural Adaptation, and Reliability and Validity Testing of a Chinese Version of the Freezing of Gait Questionnaire (FOGQ-CH)

Frontiers in Neurology, 2021
Freezing of gait is a disabling symptom with a complex episodic nature that is frequently experienced by people with Parkinson's disease (PD). Although China has the largest population with PD in the world, no Chinese version of the freezing of gait ...
Ping Tao, Ping Tao, Xuerong Shao, Jie Zhuang, Zhen Wang, Yuchen Dong, Xia Shen, Xia Shen, Yunjie Guo, Xiaoyi Shu, Hong Wang, Yuanhong Xu, Zhenlan Li, Zhenlan Li, Roger Adams, Jia Han, Jia Han, Jia Han   +17 more
doaj   +1 more source

Doorway‐provoked freezing of gait in Parkinson's disease [PDF]

Movement Disorders, 2011
AbstractFreezing of gait in Parkinson's disease can be difficult to study in the laboratory. Here we investigate the use of a variable‐width doorway to provoke freeze behavior together with new objective methods to measure it. With this approach we compare the effects of anti‐parkinsonian treatments (medications and deep‐brain stimulation of the ...
Dorothy Cowie, Patricia Limousin, Amy Peters, Marwan Hariz, Brian L. Day   +4 more
openaire   +2 more sources

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source