Results 31 to 40 of about 379,453 (310)

LEF2 - A strategic freight transport model for Great Britain. [PDF]

open access: yes, 2005
INTRODUCTION This paper reports some innovative model building that yields a useful addition to models of freight in Great Britain. Currently, the Great Britain Freight Model (GBFM) is part of the Department for Transport's (DtT) national model suite ...
Fowkes, A.S.   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Railway freight transport and logistics: Methods for relief, algorithms for verification and proposals for the adjustment of tunnel inner surfaces [PDF]

open access: yes, 2018
In Europe, the attention to efficiency and safety of international railway freight transport has grown in recent years and this has drawn attention to the importance of verifying the clearance between vehicle and lining, mostly when different and ...
Ferraro, Ricardo   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Internal report cluster 1: Urban freight innovations and solutions for sustainable deliveries (2/4) [PDF]

open access: yes, 2014
Technical report about sustainable urban freight solutions, part 2 of
Browne, M.   +3 more
core   +3 more sources

Infrastructural, Decisional and Organizational Aspects to Use Mode Shift to Handle Disruptions in Freight Transport: Literature and Expert Survey

open access: yesIEEE Open Journal of Intelligent Transportation Systems, 2021
Freight transport disruptions in recent years caused production shutdowns in the industry, supply shortages and high economic damage around the world. In practice, contingency strategies from transport operators are often weak and disruption management ...
Jan Lordieck, Francesco Corman
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Freight Transport Costs Model Based on Truck Fleet Operational Parameters

open access: yesPromet (Zagreb), 2004
The road freight transport costs are a function of numerousfactors that could be grouped according to their characteristicsand level of utilization of company's technical and human potential.The different input prices, product characte1istics ...
Mirsad Kulović
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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