Results 51 to 60 of about 68,859 (313)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Value proposition in international freight : the contribution of the freight forwarder to the global logistics triad [PDF]
The freight forwarder has been threatened with 'disintermediation' for years. This research looks at the relationships in the global logistics triad comprising the forwarder, the shipper, and the airline or ocean carrier.
Ford, Richard
core
Electrical System Design of FXN5C AC Drive Freight Diesel Locomotive
The design background of the FXN5C AC drive freight diesel locomotive was roughly described, and the con figuration, main technical parameters, traction and brake characteristics of the locomotive were brie fly described. The main transmission system, AC
Lanfeng MEI +3 more
doaj
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The present study identifies the influence of a series of factors in order to determine operating freight rates for soybeans originally grown in the States of Goiás, Mato Grosso and Paraná, during the high seasons of 1998 to 2000 and low seasons of 1998/
Goncilio Correa Junior +1 more
doaj
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
APPLICATION OF INFORMATION TECHNOLOGIES IN INTERNATIONAL CARGO CARRIAGE
Railway carriage is the main type of long-haul traffic in international carriage, thus, the key part of cargo turnover accounts for railway traffic. This makes it relevant to develop and actualize the Russian export potential by means of consolidating ...
Nina F. Sirina, Valeriy V. Zubkov
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source

