Results 51 to 60 of about 29,294 (315)

The Development of a Freight Distribution Model for Connecting Inter-island Freight Transport

International Journal of Technology, 2015
Inter-island freight transport costs in eastern compared to western Indonesia are relatively high, caused by operator charges for roundtrip fees. In order to make the distribution of freight efficient, the network of freight transport needs to be ...
Imam Sonny, Sigit P. Hadiwardoyo, Bambang Susantono, Abdellatif Benabdelhafid   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Comparing freight transport strategies and measures in London and Paris [PDF]

, 2007
The paper compares the approach being taken to freight transport strategy and the specific policy measures being implemented in London and Paris. It highlights the serious consideration that has been given to freight transport by the Mayors of London and
Attlassy, M., Browne, M., Allen, J.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Measuring the quality impacts on the performance in transport company [PDF]

Transport Problems, 2015
The paper deals with the problem of service quality, quantification of the level of quality and evaluation of service quality in freight road transport companies. The impact of the transport service quality on the performance of road freight transport is
Ivana ŠIMKOVÁ, Vladimír KONEČNÝ, Štefan LIŠČÁK, Ondrej STOPKA   +3 more
doaj  

South Africa’s rising logistics costs: An uncertain future

Journal of Transport and Supply Chain Management, 2014
A country’s competitiveness can be severely hampered by an uncompetitive freight logistics system. During the first decade of the 21st century, two in-depth models were developed for South Africa which provide a framework for measuring and improving the ...
Jan H. Havenga, Zane P. Simpson, Anneke de Bod, Nadia M. Viljoen   +3 more
doaj   +1 more source

Applying technological organization environmental model to examine the adopting intention of e-freight for the air freight forwarder [PDF]

Journal of International Logistics and Trade, 2016
The e-freight program launched by the International Air Transport Association (IATA) has gradually become a standard specification for international air freight operations.
Ching-Cheng Chao, Fang-Yuan Chen, Ching-Chiao Yang, Chien-Yu Chen   +3 more
doaj   +1 more source

Decarbonising Urban Freight Transport: Experimentations in European Research Projects [PDF]

, 2016
One of the objectives of European research programs is to decarbonize freight transport while maintaining its competitiveness and economic strength, reduce negative externalities such as pollutant emissions, congestion and accidents, and foster ...
Ruesch, M., Leonardi, J., Dablanc, L., Bohne, S., Rizet, C.   +4 more
core