Results 61 to 70 of about 29,294 (315)
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
InfrastructuresThe railway infrastructure projects in Thailand aim to shift transportation from roads to railways. This is crucial for transporting goods in emerging economies and increasing the demand for rail freight transport.
Oranicha Buthphorm +2 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke +5 more
wiley +1 more source
Analyzing loss aversion and diminishing sensitivity in a freight transport stated choice experiment [PDF]
Choice behaviour might be determined by asymmetric preferences whether the consumers are faced with gains or losses. This paper investigates loss aversion and diminishing sensitivity, and analyzes their implications on willingness to pay and willingness ...
David A. Hensher, Lorenzo Masiero
core +3 more sources
Diagnosis of Transport Activity as a Component of the Enterprise Logistical System [PDF]
Problemi Ekonomiki, 2016 The article reveals the essence of the concept of “diagnosis of the enterprise transport activity”, by which there should be meant a process of evaluating the state of movement (transportation, carrying) of freight (material resources, work in process
Skrynkovskyy Ruslan M. +3 more
doaj
Decoupling economic development and freight for reducing its negative impacts [PDF]
This paper takes a look at the development of freight transport and its further perspectives in thelight of environmental sustainability. It clearly challenges the traditional view that furthergrowth in freight transport is indispensable whatever stage ...
Pastowski, Andreas
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Financing and Deploying Automated Freight Systems [PDF]
New technologies are bringing Automated Freight Systems (AFS), which aim to reduce congestion, mitigate environmental impacts and enhance public safety, to fruition.
Xi Zou, David Levinson
core
An overview of freight intelligent transportation systems [PDF]
, 2013 The purpose of this paper is to provide an overview of how the intelligent transportation system (ITS) supports freight transportation operations. A study of the literature on transportation information and communication technology (ICT) and intelligent (
Mirza Beiki, Vahid, +2 more
core +1 more source