Results 81 to 90 of about 4,059,547 (363)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Withholding or withdrawal of treatment under French rules: a study performed in 43 intensive care units

open access: yesAnnals of Intensive Care, 2015
BackgroundIn France, decisions to limit treatment fall under the Leonetti law adopted in 2005. Leading figures from the French world of politics, science, and justice recently claimed for amendments to the law, considering it incomplete.
O. Lesieur   +3 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

European Union and Transatlantic Relations: Rotating Presidencies of France, Czech Republic and Sweden

open access: yesAnkara Avrupa Çalışmaları Dergisi, 2011
Avrupa Birliği ve Amerika Birleşik Devletleri arasındaki ilişki, taraflar için daima stratejik bir öneme sahip olmuştur ve ikili arasındaki ilişki değişen AB Dönem Başkanlıklarında farklı şekiller almıştır.
Dilek Morgül
doaj   +1 more source

Quality Assessment of the French OpenStreetMap Dataset

open access: yesTrans. GIS, 2010
The concept of Volunteered Geographic Information (VGI) has recently emerged from the new Web 2.0 technologies. The OpenStreetMap project is currently the most significant example of a system based on VGI.
Jean-François Girres, G. Touya
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

“Cinema, Alone”/Multiple “Cinemas”

open access: yesAlphaville: Journal of Film and Screen Media, 2013
This lecture was presented as part of a series of twenty-five conferences on cinema and the arts held between 2001–2002 at the Collège d’Histoire de l’Art Cinématographique, Cinémathèque française.
Raymond Bellour
doaj   +1 more source

Chikungunya Outbreak, French Polynesia, 2014

open access: yesEmerging Infectious Diseases, 2015
To the Editor: Chikungunya virus (CHIKV), an arthropod-borne virus (arbovirus) of the family Togaviridae, genus Alphavirus, is transmitted by mosquitoes of the Aedes genus, especially Ae. aegypti and Ae. albopictus (1).
M. Aubry   +10 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

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