Time and frequency domain analysis of physiological features during autonomic dysreflexia after spinal cord injury. [PDF]
Front Neurosci, 2023 Kirby AK +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Frequency-domain analysis of fNIRS fluctuations induced by rhythmic mental arithmetic. [PDF]
Psychophysiology, 2022 Molina-Rodríguez S +3 more
europepmc +1 more source
Pulse analysis of acoustic emission signals [PDF]
A method for the signature analysis of pulses in the frequency domain and the time domain is presented. Fourier spectrum, Fourier transfer function, shock spectrum and shock spectrum ratio were examined in the frequency domain analysis, and pulse shape ...
Houghton, J. R., Packman, P. F.
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A Frequency Domain Analysis of the Excitability and Bifurcations of the FitzHugh-Nagumo Neuron Model. [PDF]
J Phys Chem Lett, 2021 Bisquert J.
europepmc +1 more source
SUSSA ACTS: A computer program for steady and unsteady, subsonic and supersonic aerodynamics for aerospace complex transportation systems [PDF]
The computer program SUSSA ACTS (Steady and Unsteady, Subsonic and Supersonic Aerodynamics for Complex Transportation Systems) are presented in the final version.
Morino, L., Tseng, K.
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Comprehensive Engineering Frequency Domain Analysis and Vibration Suppression of Flexible Aircraft Based on Active Disturbance Rejection Controller. [PDF]
Sensors (Basel), 2022 Liu L, Tian B.
europepmc +1 more source