Results 101 to 110 of about 2,595,447 (316)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Advanced control and management functionalities for multi-microgrids

, 2011
This paper addresses the extension of the microgrid concept, following a massive integration of these active cells in power distribution networks, by adopting a coordinated management strategy together with distributed generation units directly connected
Lopes, JAP, Korres, GN, Hatziargyriou, ND, J. A. Peças Lopes, N. D. Hatziargyriou, A. G. Madureira, G. N. Korres, Gil, NJ, J. C. Pereira, Madureira, AG, N. J. Gil, Pereira, JC   +11 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Large-Eddy Simulation of Flow Separation and Control on a Wall-Mounted Hump [PDF]

, 2009
Active flow control techniques such as synthetic jets have been successful in increasing the performance of naturally separating flows on post-stall airfoils, bluff body shedding, and internal flows such as wide-angle diffusers.
Franck, Jennifer Ann
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Implementation of an optical fiber frequency distribution via commercial DWDM

, 2016
The rapid development in communication infrastructure over the past decades entails an increasing dependence on time and frequency, as well as its redundant distribution.
Hedekvist, Per Olof, Karlsson, Magnus, Hedekvist, Per Olof E,, Ebenhag, S. C., Sven-Christian Ebenhag, Zelan, M., Ebenhag, Sven-Christian,, Hedekvist, Per Olof,, Karlsson, Magnus,, Ebenhag, Sven-Christian, Zelan, Martin,, Zelan, M.,, Per Olof Hedekvist, Hedekvist, Per Olof E, Martin Zelan, Magnus Karlsson   +15 more
core   +1 more source

A new passive repetitive controller for discrete-time finite-frequency positive-real systems [PDF]

, 2007
This work proposes a new repetitive controller for discrete-time finite-frequency positive-real systems which are required to track periodic references or to attenuate periodic disturbances.
Costa Castelló, Ramon, Griñó Cubero, Robert, Wang, Danwei   +2 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source