Results 121 to 130 of about 2,595,447 (316)

Modeling dynamic frequency control with power reserve limitations

open access: yes, 2018
The frequency variation of a power system depends on the relationship between power generation and consumption. Increase in loads, losses or inclusion of renewable energies will lead to inaccurate controllability of the network frequency, which is the ...
Nouri, Hassan
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Frequency domain iterative feedforward/feedback tuning for MIMO ANVC

open access: yes, 2010
A new gradient estimation method is proposed that relies on efficient computation of the negative gradient of the average linear quadratic cost function completely in the frequency domain.
Veres, Sandor M.   +3 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

MPC-based Control Interface Development for Frequency Control Design with PSCAD/MATLAB

open access: yes
Frequency control is crucial for the stable operation of a power system. Among various control methodologies, model predictive control (MPC) is one of the promising methods for frequency control considering the system constraints and uncertainties ...
Saha, TK, Zhou, A, Ma, N, Bai, F
core   +1 more source

On feasibility of regional frequency-based emergency control plans

open access: yes, 2009
Decentralized and regional load-frequency control of power systems operating in normal and near-normal conditions has been well studied; and several analysis/synthesis approaches have been developed during the last few decades. However in contingency and
Bevrani, H   +7 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Testing speed of light isotropy using rotating cryogenic sapphire microwave oscillators

open access: yes, 2014
Technical paperWe will present an update on the latest rotating cryogenic sapphire oscillator experiment, currently located at Humboldt University of Berlin (HUB). © 2014 IEEE.Stephen R. Parker, Moritz Nagel, Evgeny Kovalchuk, Paul L.
Evgeny Kovalchuk   +15 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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