Results 101 to 110 of about 5,431,466 (351)

Performance analysis of shearer driven by motor and hydraulic torque converter

Gong-kuang zidonghua, 2018
Currently shearer is mainly driven by motor and frequency converter, and it is difficult to meet requirement of larger output torque when cutting complex coal seam at low speed. In view of the problem, performance of shearer driven by motor and hydraulic
WU Senfeng
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Metamaterial Polarization Converter Analysis: Limits of Performance

, 2012
In this paper we analyze the theoretical limits of a metamaterial converter that allows for linear-to- elliptical polarization transformation with any desired ellipticity and ellipse orientation.
A. Drezet, A. Pors, A. Roberts, A.C. Strikwerda, A.C. Strikwerda, Andrei Andryieuski, Andrei V. Lavrinenko, C. Sabah, D. Molter, D.-H. Kwon, Dmitry L. Markovich, F. Wang, J. Hao, J. Hao, J.B. Masson, J.K. Gansel, J.Y. Chin, J.Y. Chin, M. Mutlu, M. Tonouchi, Maksim Zalkovskij, P. Weis, P.U. Jepsen, R. Singh, Radu Malureanu, S.C Saha, S.X. Li, T. Arikawa, T. Kleine-Ostmann, T. Li, W. Sun, X.G. Peralta, Y. Zhao   +32 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Application of Modbus Protocol in Communication between S7-226 PLC and Lenze Frequency Converter

Gong-kuang zidonghua, 2011
In view of problem of distortion of signal of long-distance transmission when using conventional switch quantity, analogue control method to control frequency converter, the paper put forward a method which adopted Modbus protocol to communicate between ...
ZHANG Zhi-wei, ZHANG Shi-cong, WANG Ran-feng   +2 more
doaj  

Introduction of a novel frequency converter using piezoelectric vibrations modes. [PDF]

Sci Rep, 2023
Pirayande A, Hojjat Y.
europepmc   +1 more source

The Questions of Circuitry Design when Forming the Switching Functions of the Control System of the Matrix Frequency Converter

, 2015
The switching function generator of the matrix frequency converter control system is described. This device can be used in the control systems of frequency-controlled AC drives and special consumers.
A. Bondarev, S. Fedorov, E. Muravyova, R. Kadyrov, E. A. Shulaeva   +4 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Design and Implementation of Σ-ΔADC Converter Based on FPGA

Gong-kuang zidonghua, 2012
For problems that instantaneous sampling method is only suitable for occasions that frequency converter analog is more smooth and sampling frequency is higher, and average value sampling method requires high sampling frequency and fast operation, a Σ ...
ZHANG Bo
doaj