Results 71 to 80 of about 413,674 (286)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Bias-Reduced Localization for Drone Swarm Based on Sensor Selection

Sensors
To address the problem of accurate localization of high-speed drone swarm intrusions, this paper adopts time difference of arrival (TDOA) and frequency difference of arrival (FDOA) measurements, aiming to improve the performance of estimating the motion ...
Bo Wu, Bazhong Shen, Yonggan Zhang, Li Yang, Zhiguo Wang   +4 more
doaj   +1 more source

Fast TDOA and FDOA Estimation for Coherent Pulse Signals

International Journal of Antennas and Propagation, 2022
Time difference of arrival (TDOA) and frequency difference of arrival (FDOA) have been widely used for localizing temporally continuous signals passively.
Yan Liu, Fucheng Guo
doaj   +1 more source

Two-Dimensional Frequency-Difference-of-Arrival Varieties

This paper studies Frequency-Difference-of-Arrival (FDOA) curves for the 2-dimensional, 2-sensor case. The primary focus of this paper is to give a description of curves associated to the FDOA problem from the algebro-geometric point of view. To be more precise, the complex projective picture of the family of FDOA curves for all possible relative ...
Duflot, Jeanne, Cheney, Margaret, Given, James A.   +2 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Sensitivity of new detection method for ultra-low frequency gravitational waves with pulsar spin-down rate statistics

, 2018
A new detection method for ultra-low frequency gravitational waves (GWs) with a frequency much lower than the observational range of pulsar timing arrays (PTAs) was suggested in Yonemaru et al. (2016).
Kumamoto, Hiroki, Kuroyanagi, Sachiko, Takahashi, Keitaro, Yonemaru, Naoyuki   +3 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

What brakes the Crab pulsar? [PDF]

, 2015
Optical observations provide convincing evidence that the optical phase of the Crab pulsar follows the radio one closely. Since optical data do not depend on dispersion measure variations, they provide a robust and independent confirmation of the radio ...
Barbieri, C., Barbieri, M., Calvani, M., Naletto, G., Ponikvar, D., Zampieri, L., Čadež, A.   +6 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source