Results 71 to 80 of about 64,399 (240)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Distributed Passive Tracking of a Non-Cooperative Underwater Target Utilizing Temporal Correlation of Line Spectrum

open access: yesJournal of Marine Science and Engineering
Distributed passive acoustic tracking is an important technique for detecting and localizing a non-cooperative underwater target, in which the frequency difference of arrival (FDOA) is a widely used measurement.
Shutong Zong, Wei Gao, Xiaolei Li
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Improving the Error of Time Differences of Arrival on Partial Discharges Measurement in Gas-Insulated Switchgear

open access: yesSensors, 2018
Partial Discharge (PD) detection based on Ultra-High-Frequency (UHF) measurements in Gas-Insulated Switchgear (GIS) is often used for fault location based on extraction of Time Differences of Arrival (TDoA), and the core technique is to obtain the ...
Jun Jiang   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A Hybrid Distance Estimation for Wireless Body Sensor Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2013
Wireless body area networks become a new research issue in recent years. In this paper, we propose hibernation and distance estimation schemes for wireless USB (WUSB) over wireless body area networks (WBAN) hierarchical protocol for body sensor networks (
Kyeong Hur, Won-Sung Sohn, Jae-Kyung Kim
doaj   +1 more source

RSSI-Power-Based Direction of Arrival Estimation of Partial Discharges in Substations

open access: yesEnergies, 2019
The localization of partial discharges in air-insulated substations using ultra-high frequency technology is widely studied for power equipment early warning purposes.
Fan Wu   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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