Results 101 to 110 of about 38,141 (258)

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang   +4 more
wiley   +1 more source

Electrical Impedance Myography Detects Disease Progression over 12 to 24 Months in Facioscapulohumeral Muscular Dystrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Targeted therapies for facioscapulohumeral muscular dystrophy (FSHD) are progressing through clinical trials. Electrical impedance myography (EIM) provides a noninvasive biomarker of muscle composition that may be valuable especially in early phase trials. This study evaluated EIM data from a multicenter FSHD cohort over 24 months.
Karlien Mul   +15 more
wiley   +1 more source

The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report. [PDF]

open access: yes, 2016
The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium is a novel, interdisciplinary initiative comprised of experts across many fields, including genomics, data analysis, engineering, public health, and ...
MetaSUB International Consortium
core   +1 more source

Augmenting adaptive immunity: progress and challenges in the quantitative engineering and analysis of adaptive immune receptor repertoires

open access: yes, 2019
The adaptive immune system is a natural diagnostic and therapeutic. It recognizes threats earlier than clinical symptoms manifest and neutralizes antigen with exquisite specificity.
Abbas   +478 more
core   +1 more source

Joint Decoupling Optimization of Frequency Offsets and Array Elements for Frequency Diverse Arrays

open access: yesInternational Journal of Antennas and Propagation
Frequency diverse array (FDA) has a distance-angle–dependent beam direction map, which has a greater application advantage than phased array. However, due to the distance-angle coupling and periodicity of its beam direction map, it makes the parameter ...
Yuming Lu   +4 more
doaj   +1 more source

Responding to Agency Avoidance of OIRA [PDF]

open access: yes, 2014
Concerns have recently been raised that US federal agencies may sometimes avoid regulatory review by the White House Office of Information and Regulatory Affairs (OIRA).
Mendelson, Nina A., Wiener, Jonathan B.
core   +2 more sources

Frequency Diverse Array Radar Signal Processing via Space-Range-Doppler Focus (SRDF) Method

open access: yesLeida xuebao, 2018
To meet the urgent demand of low-observable moving target detection in complex environments, a novel method of Frequency Diverse Array (FDA) radar signal processing method based on Space-Rang-Doppler Focusing (SRDF) is proposed in this paper. The current
Chen Xiaolong   +4 more
doaj   +1 more source

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai   +9 more
wiley   +1 more source

Improving the Quality and Efficiency of the Medicare Program Through Coverage Policy [PDF]

open access: yes, 2011
Outlines Medicare coverage and payment policy on new technologies and recommends changes that could help achieve the Triple Aim goals of enhancing the individual experience of care, improving population health, and reducing per capita costs of ...
Penny E. Mohr   +3 more
core  

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

open access: yesBMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia   +9 more
wiley   +1 more source

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