Results 171 to 180 of about 41,729 (299)

From concept to clinic: a roadmap for DNA methylation biomarkers in liquid biopsies. [PDF]

Oncogene
Pharo H, Vedeld HM, Sjurgard IV, Pinto R, Lind GE.   +4 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Addressing the challenges of immunogenicity, heterogeneity and tumorigenicity in the clinical translation of human embryonic stem cells. [PDF]

Stem Cell Res Ther
Xia L, Qin J, Ye S.
europepmc   +1 more source

Transforming Fragile Hydrogel Chips Into Standardized Cartridges via Contact Line Pinning for Robust Microfluidics

Small, EarlyView.
Hydrogel‐based microfluidic chips revolutionize drug delivery, tissue engineering, and biosensing, yet face challenges due to fragility and connection difficulty. This study introduces a novel cartridge design that enhances usability through a hydrogel–plastic hybrid design and a contactless connection method.
Sin‐Yung Siu, Chiu‐Wing Chan, Yisu Wang, Langcheng Feng, Yichen Su, Yin Chen, Christopher K C LAI, Pingan Zhu, Kangning Ren   +8 more
wiley   +1 more source

A conformal piezoelectric microsystem for demographic-adaptive and calibration-free cuffless blood pressure monitoring. [PDF]

Nat Commun
Liang C, Jiang Z, Qiu S, Zhao L, Mao X, Yang X, Zhang Y, Zhao N.   +7 more
europepmc   +1 more source

Nanomaterial‐Based Inkjet Printing for Electrochemical Sensing

Small, EarlyView.
Inkjet printing provides a digitally controlled, versatile, and highly reproducible method for fabricating and functionalizing sensing devices. This Perspective highlights how homogeneous, material‐efficient deposition enables precise patterning of functional inks and scalable integration of sensors for chemical and biological detection. The discussion
David Panáček, Massimo Urban, Alessandro Silvestri, Ivan Dědek, Martin‐Alex Nalepa, Arben Merkoçi, Maurizio Prato, Michal Otyepka   +7 more
wiley   +1 more source

Clinical translation of fluid, imaging, and digital biomarkers for Alzheimer's disease. [PDF]

Alzheimers Res Ther
Bacci JR, Karagianni S, Alexopoulou ZS, Moukaled S, Tato-Fernández C, Arunachalam P, Aslanyan A, Aye S, Rocha ASL, Crugel M, Fawad A, Sogorb-Esteve A, Schöll M, König A, Paterson RW.   +14 more
europepmc   +1 more source

f‐Block Element‐Based MOF Thin Films: A Platform for Luminescence, Sensing, and Energy Applications

Small, EarlyView.
f‐Block element–based metal–organic framework (f‐MOF) thin films offer exceptional potential for luminescent, sensing, and energy‐related applications. This review surveys recent progress in their synthesis, characterization, and functional implementation, emphasizing the diversity of available thin‐film fabrication strategies. The convergence of these
Dong‐Hui Chen, Christof Wöll
wiley   +1 more source

Physician Antibiotic Prescribing Preferences in Community Acquired Pneumonia and Complicated Urinary Tract Infections: A National Discrete Choice Experiment. [PDF]

Open Forum Infect Dis
Hong D, Kesselheim AS, Metlay JP, Powers JH, Morlock R, Feldman WB.   +5 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source