Results 171 to 180 of about 38,141 (258)

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Consensus Guidelines for the Use of Peripheral Nerve Stimulation in the Treatment of Chronic Pain and Neurological Diseases: A Neuron Project from the American Society of Pain and Neuroscience. [PDF]

J Pain Res
Latif U, Moghim R, Valimahomed A, Lam CM, Abd-Elsayed A, Gulati A, Aman MM, Desai MJ, Dickerson DM, Tieppo Francio V, Gilmore C, Gish B, Hah JM, Hunter C, Ilfeld BM, Kalia H, Lester D, Li S, Mata R, Naidu R, Ottestad E, Pritzlaff SG, Schatman ME, Sheth SJ, Slavin KV, Suvar T, Yalamuru B, Staats PS, Sayed D, Deer TR.   +29 more
europepmc   +1 more source

Implementation of OMOP and ConcePTION Common Data Models in CPRD GOLD: Risk of Bleeding and Cardiovascular Outcomes From Anticoagulant Use

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1574-1583, June 2026.
The impact of the choice of common data model (CDM) approach on the study results in a real‐world evidence (RWE) study is unknown. We aimed to determine potential differences in the results of an RWE study when data were mapped to two different CDMs, ConcePTION and OMOP. With the same instance of CPRD GOLD, data were mapped to both CDMs. Using the same
Nicholas B. Hunt, Patrick Souverein, Marloes Bazelier, Nicola Barclay, Antonella Delmestri, Miriam Sturkenboom, Daniel Prieto‐Alhambra, Helga Gardarsdottir, Olaf Klungel   +8 more
wiley   +1 more source

Transforming healthcare through in-body bioelectronic systems. [PDF]

Nat Commun
Ceto S, Elshove SA, Wu M, Ramadi K, Tondera C, Minev IR, Srinivasan S, Lee K, Gora MJ, Rogers J, Kathe C, Hutson TH.   +11 more
europepmc   +1 more source

Microbial Safety of Legumes—A Review: Bacterial Contamination, Foodborne Outbreaks, and Traditional and Innovative Mitigation Strategies

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Demand for plant‐based foods, including legumes, is growing as a result of consumer preferences shifting toward food sustainability and plant‐based, protein‐rich foods. However, to ensure the food safety of such alternatives, assessing the prevalence of foodborne pathogens related to these products is critical, especially with their increasing
Natoavina T. Faliarizao, Narindra Randriamiarintsoa, Teresa M. Bergholz, Kirk D. Dolan   +3 more
wiley   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source

Patient-centered gastrointestinal function assessment technologies: a paradigm shift from traditional approaches to non-invasive innovations. [PDF]

Front Physiol
Zhu Q, Li Q, Zan Y, Lu Y, Xia L, Xia Y, Xu T.   +6 more
europepmc   +1 more source

Real‐World Patient Characteristics and Treatment Patterns Among Patients With Interstitial Cystitis (IC)/Bladder Pain Syndrome (BPS)

Reproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Objective Interstitial cystitis/bladder pain syndrome (IC/BPS) is linked to bladder and/or pelvic pain, pressure, and discomfort with urinary frequency. Despite guidelines, there is a need for better treatment options. This study analyzed patient demographics, clinical characteristics, and treatment patterns for medications and procedures in ...
Jaromir Mikl, Tiange Yu, Benjamin T. Carter, Andrew Rava, Xin Zhao, Catherine Allende, Amie Devlin, Valentine Pascale, Roger Dmochowski   +8 more
wiley   +1 more source

Recent Advances in Wearable Biosensors for Human Health Monitoring. [PDF]

Biosensors (Basel)
Xian X.
europepmc   +1 more source

Large Language Models for Explainable Medical Text Summarization: A Systematic Literature Review

WIREs Data Mining and Knowledge Discovery, Volume 16, Issue 2, June 2026.
The graphical abstract highlights the three key aspects addressed in this review: the technical background of medical text summarization methods relevant to clinical decision support; the LLM background in providing context for its diagnosis and clinical significance; and clinical decision support with summarization and explainability in patient care ...
Aleka Melese Ayalew, Md Rabiul Hasan, Tapio Seppänen, Mourad Oussalah   +3 more
wiley   +1 more source