Hematological toxicities and thrombosis risk associated with immune checkpoint inhibitors: a pharmacovigilance study from 2014 to 2024. [PDF]
Hou J, Mu G, Zhang Z, Xiang Q, Cui Y.
europepmc +1 more source
Nanotechnology Meets Immunotherapy: Crosstalks Against Cancer
ABSTRACT Background The convergence of nanotechnology and immunotherapy has ushered in a transformative era in cancer treatment, offering new strategies to overcome pharmacokinetic limitations and immune evasion associated with conventional therapies. While immunotherapy, spanning checkpoint inhibitors, adoptive cell transfer, and cancer vaccines, has ...
Nima Javanmehr +4 more
wiley +1 more source
Novel Liquid Biopsy in Gastrointestinal Cancers. [PDF]
Chang LC, Shen TL, Ochiya T.
europepmc +1 more source
ABSTRACT Stem cell therapy is currently undergoing clinical research in China for conditions that are resistant to or incurable by traditional pharmaceutical interventions. Stem cell‐derived extracellular vesicles (EVs) exhibit therapeutic effects similar to those of their parent stem cells, positioning them as an alternative or adjunctive approach to ...
Tao Na +9 more
wiley +1 more source
Beyond CAR-T and oncology: broadening chimeric antigen receptor technologies across cell types and diseases. [PDF]
Liu X, Gao H, Yu J.
europepmc +1 more source
Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang +6 more
wiley +1 more source
Clinical translation of photoacoustic imaging using exogenous molecular contrast agents [Invited]. [PDF]
Miao J +6 more
europepmc +1 more source
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source
Acoustic emissions dose and spatial control of blood-brain barrier opening with focused ultrasound. [PDF]
Woodworth GF +20 more
europepmc +1 more source
Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between
This review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
Marcela de Sá Barreto da Cunha +5 more
wiley +1 more source

