Results 81 to 90 of about 5,319,308 (296)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

New design method of space-frequency coding and fast detection algorithm

open access: yesTongxin xuebao, 2009
To analyze the performance of space-frequency codes,the Chernoff bound was used in the existing literatures,but it was too loose to conclude the diversity order and coding gain simultaneously.Therefore,a new view of the transmission of space-frequency ...
WANG Xin, WEI Ji-bo, LI Ying
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Frequency-Domain Diversity Combining Receiver for ACO-OFDM System

open access: yesIEEE Photonics Journal, 2015
This paper proposes a new receiver based on frequency-domain diversity combining (FDDC) for an asymmetrically clipped optical orthogonal frequency-division multiplexing (ACO-OFDM) system.
J. Dang, Z. Zhang, L. Wu
doaj   +1 more source

Frequency Diverse Coprime Arrays With Coprime Frequency Offsets for Multitarget Localization

open access: yesIEEE Journal of Selected Topics in Signal Processing, 2017
Different from conventional phased-array radars, the frequency diverse array (FDA) radar offers a range-dependent beampattern capability that is attractive in various applications. The spatial and range resolutions of an FDA radar are fundamentally limited by the array geometry and the frequency offset.
Si Qin   +3 more
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Profiling lexical diversity in college-level writing

open access: yesVocabulary Learning and Instruction
The present paper reports on a study that examined the contribution of lexical frequency to lexical diversity in narrative texts composed by 119 multilingual and monolingual English-speaking students enrolled in first-year college writing courses.
Melanie C. González
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Cost effective estimation and equalization of frequency selective channels for transmit diversity

open access: yes, 2011
In this paper we propose a novel receiver for multiple input single output channels. Such approaches are preferred in boosting the diversity within the channel, to combat fading.
Kale, I., Coskun, A.
core   +1 more source

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