Results 121 to 130 of about 1,219,269 (316)

Normalized Study of Three-Parameter System in the Time Domain and Frequency Domain

open access: yesShock and Vibration, 2017
Three-parameter isolation system can be used to isolate microvibration for control moment gyroscopes. Normalized analytical model for three-parameter system in the time domain and frequency domain is proposed by using analytical method.
Xiao-Lei Jiao, Yang Zhao, Wen-Lai Ma
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Realisations of Finite-Sample Frequency-Selective Filters [PDF]

open access: yes
A filtered data sequence can be obtained by multiplying the Fourier ordinates of the data by the ordinates of the frequency response of the filter and by applying the inverse Fourier transform to carry the product back to the time domain.
D.S.G. Pollock
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Color vision in the comb frequency domain

open access: yesBiological Research, 2003
In 1982, Horace Barlow considered the question of human trichromacy in the context of information theory: according to the Sampling Theorem, three types of receptors covering the visible spectrum (400- -700 nm) might be sufficient to reconstruct the ...
VALÈRIE BONNARDEL, FRANCISCO J. VARELA
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Multiuser Decorrelating Based Long-Range Frequency-Domain Channel Transfer Function Prediction in Multicarrier DS-CDMA Systems

open access: yes, 2006
In this contribution, multiuser decorrelating based frequency-domain channel estimation and long range channel prediction techniques are proposed for a generalized Multicarrier DS-CDMA (MC DS-CDMA) system communicating over a fast fading and frequency ...
Yang, L.-L., Liu, W., Hanzo, L., Hu, B.
core  

Comparison of Frequency Domain and Time-Domain Methods for Aeromechanical Analysis

open access: yesInternational Journal of Rotating Machinery, 2016
Unsteady flow around an oscillating plate cascade and that through a single compressor rotor subject to vibration have been computationally studied, aimed at examining the predictive ability of two low fidelity frequency methods compared with a high ...
M. T. Rahmati
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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