Results 81 to 90 of about 2,463,245 (334)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Electro-optic network analyzer [PDF]

open access: yes
The bandwidth of frequency domain measurement methods of electrical signals has usually been far greater than the bandwidth of time domain methods. The primary limits of the time domain approach have been the 20 to 30 GHz bandwidth limit for electronic ...
Jackson, Todd A.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Efficient Analysis of Ferrite Loaded Waveguides Using the MRFD Method [PDF]

open access: yes, 2012
A full wave two-dimensional Multiresolution Frequency Domain formulation for efficient analysis of the dispersion characteristics of ferrite loaded waveguide structures is developed and presented.
Gokten, M.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Spectral domain analysis of double screen frequency selective surfaces

open access: yesJournal of Microwaves, Optoelectronics and Electromagnetic Applications
This paper presents a numerical investigation for a double screen frequency selective surface (FSS) with perfectly conducting rectangular patch elements. The analysis uses a full wave technique to obtain the scattering characteristics.
Antonio Luiz Pereira de Siqueira Campos   +1 more
doaj   +1 more source

Frequency domain based DC fault analysis for bipolar HVDC grids

open access: yesJournal of Modern Power Systems and Clean Energy, 2017
This paper proposes a frequency domain based methodology to analyse the influence of High Voltage Direct Current (HVDC) configurations and system parameters on the travelling wave behaviour during a DC fault.
Mian WANG, Jef BEERTEN, Dirk Van HERTEM
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Analytic structure of radiation boundary kernels for blackhole perturbations

open access: yes, 2005
Exact outer boundary conditions for gravitational perturbations of the Schwarzschild metric feature integral convolution between a time-domain boundary kernel and each radiative mode of the perturbation. For both axial (Regge-Wheeler) and polar (Zerilli)
Chandrasekhar S.   +6 more
core   +1 more source

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