Results 51 to 60 of about 499,713 (313)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

THE STRUCTURE OF THE FREQUENCY EQUATIONS ROD SYSTEMS WITH DISTRIBUTED PARAMETERS

open access: yesNauka ta progres transportu, 2009
The graph and finite-state machine models for forming spatial vibration frequency equations with continuous parameters are used. The example of calculation of vibrations of bi-regular beam with different section characteristics is presented.
O. S. Raspopov
doaj  

Unified Theory Based on Parameter Scaling for Derivation of Nonlinear Wave Equations in Bubbly Liquids

open access: yesJournal of Fluid Science and Technology, 2010
We propose a systematic derivation method of the Korteweg-de Vries-Burgers (KdVB) equation and nonlinear Schrödinger (NLS) equation for nonlinear waves in bubbly liquids on the basis of appropriate choices of scaling relations of physical parameters.
Tetsuya KANAGAWA   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A Galerkin boundary element method for high frequency scattering by convex polygons [PDF]

open access: yes, 2007
In this paper we consider the problem of time-harmonic acoustic scattering in two dimensions by convex polygons. Standard boundary or finite element methods for acoustic scattering problems have a computational cost that grows at least linearly as a ...
Langdon, S, Chandler-Wilde, S N
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Entrainment of frequency in evolution equations

open access: yesJournal of Differential Equations, 1973
AbstractThe existence of periodic solutions near resonance is discussed using elementary methods for the evolution equation ·u = Au + ϵf(t, u) when the linear problem is totally degenerate (e2πA = I) and the period of f is entrained with ϵ (T = 2π(1 + ϵμ)).
Fink, James P., Hall, William S.
openaire   +1 more source

Approximation of the Wigner Distribution for Dynamical Systems Governed by Differential Equations

open access: yesEURASIP Journal on Advances in Signal Processing, 2002
A conceptually new approximation method to study the time-frequency properties of dynamical systems characterized by linear ordinary differential equations is presented.
Cohen Leon, Galleani Lorenzo
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Position Dependent Planck’s Constant in a Frequency-Conserving Schrödinger Equation

open access: yes, 2020
There is controversial evidence that Planck’s constant shows unexpected variations with altitude above the earth due to Kentosh and Mohageg, and yearly systematic changes with the orbit of the earth about the sun due to Hutchin.
Rand Dannenberg
core   +1 more source

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