Results 51 to 60 of about 4,543,260 (298)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

THE STRUCTURE OF THE FREQUENCY EQUATIONS ROD SYSTEMS WITH DISTRIBUTED PARAMETERS

Nauka ta progres transportu, 2009
The graph and finite-state machine models for forming spatial vibration frequency equations with continuous parameters are used. The example of calculation of vibrations of bi-regular beam with different section characteristics is presented.
O. S. Raspopov
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Unified Theory Based on Parameter Scaling for Derivation of Nonlinear Wave Equations in Bubbly Liquids

Journal of Fluid Science and Technology, 2010
We propose a systematic derivation method of the Korteweg-de Vries-Burgers (KdVB) equation and nonlinear Schrödinger (NLS) equation for nonlinear waves in bubbly liquids on the basis of appropriate choices of scaling relations of physical parameters.
Tetsuya KANAGAWA, Takeru YANO, Masao WATANABE, Shigeo FUJIKAWA   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Approximation of the Wigner Distribution for Dynamical Systems Governed by Differential Equations

EURASIP Journal on Advances in Signal Processing, 2002
A conceptually new approximation method to study the time-frequency properties of dynamical systems characterized by linear ordinary differential equations is presented.
Cohen Leon, Galleani Lorenzo
doaj   +1 more source

Difference‐Equation‐Based Digital Frequency Synthesizer [PDF]

Mathematical Problems in Engineering, 2012
This paper presents a novel algorithm and architecture for digital frequency synthesis (DFS). It is based on a simple difference equation. Simulation results show that the proposed DFS algorithm is preferable to the conventional phase‐locked‐loop frequency synthesizer and the direct digital frequency synthesizer in terms of the spurious‐free dynamic ...
Lu-Ting Ko, Jwu-E. Chen, Yaw-Shih Shieh, Hsi-Chin Hsin, Tze-Yun Sung   +4 more
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Frequency conversion based on three-wave parametric solitons [PDF]

, 2010
Parametric three-wave mixing in quadratic nonlinear crystals provides a versatile means of achieving widely tunable frequency conversion of laser light, thus permitting a substantial extension of the wavelength coverage of laser sources across broad ...
Degasperis, Antonio, A. DE GASPERIS, de Angelis, Costantino, Wabnitz, Stefan, DE ANGELIS C, Lombardo, Sara, S. LOMBARDO, CONFORTI M, DE GASPERIS, Antonio, Baronio, Fabio, Matteo Conforti, BARONIO F, Stefan Wabnitz, Sara Lombardo, Costantino De, Conforti, Matteo, Fabio Baronio, Antonio Degasperis   +17 more
core   +1 more source